职业自行车赛车手血浆酶活性的变化
Changes in plasma enzyme activities in professional racing cyclists.
作者信息
Mena P, Maynar M, Campillo J E
机构信息
Departmento de Fisiología, Facultad de Medicina, Universidad de Extremadura, Badajoz, Spain.
出版信息
Br J Sports Med. 1996 Jun;30(2):122-4. doi: 10.1136/bjsm.30.2.122.
OBJECTIVE
To reports changes in plasma levels in professional racing cyclists.
METHODS
Plasma levels of the intracellular enzymes aspartate aminotransferase, alanine aminotransferase, gamma glutamyl transpeptidase, lactate dehydrogenase, and alkaline phosphatase were measured resting and after exercise in professional cyclists participating in two road races: Vuelta Ciclista a Valencia (800 km, beginning of the cyclist season), and the top rank race Vuelta a España (2700 km, at the end of cyclist season).
RESULTS
A significant increase in plasma aspartate aminotransferase, alanine aminotransferase, and alkaline phosphatase was observed at the end of the race over the corresponding paired start values (P < 0.05). The increase in plasma lactate dehydrogenase after the race was only statistically significant (P < 0.05) in the Vuelta a España. The longer the duration of the cycle tour race, the greater were the increases in aspartate aminotransferase and alanine aminotransferase levels. The high levels returned to their start values during the overnight resting period.
CONCLUSIONS
The presence of these enzymes in the blood is probably due to mechanically damaged muscle cells leaking their contents into the interstitial fluid.
目的
报告职业自行车赛车手血浆水平的变化。
方法
在参加两场公路赛的职业自行车赛车手中，测量静息状态和运动后血浆中细胞内酶天冬氨酸转氨酶、丙氨酸转氨酶、γ-谷氨酰转肽酶、乳酸脱氢酶和碱性磷酸酶的水平。这两场比赛分别是：瓦伦西亚自行车赛（800公里，自行车赛季开始时）和顶级赛事环西班牙自行车赛（2700公里，自行车赛季结束时）。
结果
比赛结束时，观察到血浆中天冬氨酸转氨酶、丙氨酸转氨酶和碱性磷酸酶较相应配对的起始值显著升高（P<0.05）。比赛后血浆乳酸脱氢酶的升高仅在环西班牙自行车赛中具有统计学意义（P<0.05）。自行车巡回赛的持续时间越长，天冬氨酸转氨酶和丙氨酸转氨酶水平的升高幅度就越大。高水平在夜间休息期间恢复到起始值。
结论
血液中这些酶的存在可能是由于机械损伤的肌肉细胞将其内容物泄漏到组织液中所致。
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