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牛蒡子乙醇提取物对大鼠红细胞免疫功能影响的研究

A study on the effect of ethanol extract of Radix rhapontici on erythrocyte immune function in rats.

作者信息

Yan Xiang, Zhao Hong, Guan Yin, Song Yanbin, Meng Jing

机构信息

Medical Oncology Department of PLA General Hospital, BeiJing, China.

出版信息

Afr J Tradit Complement Altern Med. 2013 Oct 3;10(6):538-41. doi: 10.4314/ajtcam.v10i6.25. eCollection 2013.

Abstract

This paper mainly studied the effect of ethanol extract of Radix rhapontici on erythrocyte immune function in SD rats with acute blood stasis. The methods used the effect on erythrocyte immune function. After intragastric administration of suspension of ethanol extract of Radix rhapontici to SD rats for 3 weeks, on the 21st day from intragastric administration, SD rats were made into blood stasis model and bloods were collected to determine the C3b, C3bRR, RFIR, and RFER in erythrocyte immune function. Meanwhile, serum total antioxidant activity (TAA), superoxide dismutase (SOD) activity, and serum malondialdehyde (MDA) level of rats were determined, and experimental results were analysed with analysis of variance and Q test. The results showed that the ethanol extract of Radix rhapontici had a very good effect on enhancement of erythrocyte immune function in SD rats.

摘要

本文主要研究了祁州漏芦乙醇提取物对急性血瘀证SD大鼠红细胞免疫功能的影响。方法采用对红细胞免疫功能的影响。将祁州漏芦乙醇提取物混悬液灌胃给予SD大鼠3周,自灌胃第21天起,将SD大鼠制成血瘀模型并采血,测定红细胞免疫功能中的C3b、C3bRR、RFIR和RFER。同时,测定大鼠血清总抗氧化活性(TAA)、超氧化物歧化酶(SOD)活性及血清丙二醛(MDA)水平,并采用方差分析和Q检验对实验结果进行分析。结果表明,祁州漏芦乙醇提取物对增强SD大鼠红细胞免疫功能有很好的效果。

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