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Mind the gap! Connexins and pannexins in physiology, pharmacology and disease.注意差距!连接蛋白和泛连接蛋白在生理学、药理学及疾病中的作用
Front Pharmacol. 2013 Nov 21;4:144. doi: 10.3389/fphar.2013.00144. eCollection 2013.
2
Connexin and pannexin hemichannels in inflammatory responses of glia and neurons.缝隙连接蛋白和pannexin 半通道在神经胶质细胞和神经元炎症反应中的作用。
Brain Res. 2012 Dec 3;1487:3-15. doi: 10.1016/j.brainres.2012.08.042. Epub 2012 Sep 10.
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Pannexin channels are not gap junction hemichannels.缝隙连接通道不是连接子通道。
Channels (Austin). 2011 May-Jun;5(3):193-7. doi: 10.4161/chan.5.3.15765. Epub 2011 May 1.
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Roles of connexins and pannexins in (neuro)endocrine physiology.连接蛋白和泛连接蛋白在(神经)内分泌生理学中的作用。
Cell Mol Life Sci. 2015 Aug;72(15):2911-28. doi: 10.1007/s00018-015-1967-2. Epub 2015 Jun 18.
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Gap junction channels and hemichannels in the CNS: regulation by signaling molecules.中枢神经系统中的间隙连接通道和半通道:受信号分子调控
Neuropharmacology. 2013 Dec;75:567-82. doi: 10.1016/j.neuropharm.2013.02.020. Epub 2013 Mar 7.
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Biochim Biophys Acta. 2013 Jan;1828(1):4-14. doi: 10.1016/j.bbamem.2012.02.007. Epub 2012 Feb 14.
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Hemichannels: permeants and their effect on development, physiology and death.离子通道:通透离子及其对发育、生理和死亡的影响。
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Neuropharmacology. 2013 Dec;75:525-32. doi: 10.1016/j.neuropharm.2013.02.021. Epub 2013 Mar 13.
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Connexin and Pannexin (Hemi)Channels: Emerging Targets in the Treatment of Liver Disease.连接蛋白和间隙连接蛋白 (半通道):肝脏疾病治疗的新兴靶点。
Hepatology. 2019 Mar;69(3):1317-1323. doi: 10.1002/hep.30306. Epub 2019 Feb 23.
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Connexin and pannexin hemichannels of neurons and astrocytes.神经元和星形胶质细胞的连接蛋白和孔蛋白半通道。
Channels (Austin). 2008 Mar-Apr;2(2):81-6. doi: 10.4161/chan.2.2.6003. Epub 2008 Mar 29.

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Mechanical regulation of oligodendrocyte biology.少突胶质细胞生物学的机械调控
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The Opening of Connexin 43 Hemichannels Alters Hippocampal Astrocyte Function and Neuronal Survival in Prenatally LPS-Exposed Adult Offspring.连接蛋白43半通道的开放改变了产前暴露于脂多糖的成年子代海马星形胶质细胞功能和神经元存活。
Front Cell Neurosci. 2019 Oct 11;13:460. doi: 10.3389/fncel.2019.00460. eCollection 2019.
3
Heavy Alcohol Exposure Activates Astroglial Hemichannels and Pannexons in the Hippocampus of Adolescent Rats: Effects on Neuroinflammation and Astrocyte Arborization.重度酒精暴露激活青春期大鼠海马中的星形胶质细胞半通道和连接蛋白通道:对神经炎症和星形胶质细胞分支的影响。
Front Cell Neurosci. 2018 Dec 4;12:472. doi: 10.3389/fncel.2018.00472. eCollection 2018.
4
New Implications for the Melanocortin System in Alcohol Drinking Behavior in Adolescents: The Glial Dysfunction Hypothesis.黑素皮质素系统对青少年饮酒行为的新影响:神经胶质细胞功能障碍假说
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本文引用的文献

1
Managing the complexity of communication: regulation of gap junctions by post-translational modification.应对通信复杂性:通过翻译后修饰调控间隙连接
Front Pharmacol. 2013 Oct 22;4:130. doi: 10.3389/fphar.2013.00130.
2
Neurological manifestations of oculodentodigital dysplasia: a Cx43 channelopathy of the central nervous system?眼牙指发育不全的神经学表现:一种中枢神经系统的Cx43通道病?
Front Pharmacol. 2013 Sep 26;4:120. doi: 10.3389/fphar.2013.00120.
3
The effects of the histone deacetylase inhibitor 4-phenylbutyrate on gap junction conductance and permeability.组蛋白去乙酰化酶抑制剂 4-苯基丁酸对缝隙连接电导和通透性的影响。
Front Pharmacol. 2013 Sep 3;4:111. doi: 10.3389/fphar.2013.00111. eCollection 2013.
4
An Escherichia coli strain for expression of the connexin45 carboxyl terminus attached to the 4th transmembrane domain.带有连接蛋白 45 羧基末端连接到第 4 跨膜结构域的大肠杆菌菌株。
Front Pharmacol. 2013 Aug 23;4:106. doi: 10.3389/fphar.2013.00106. eCollection 2013.
5
Together and apart: inhibition of DNA synthesis by connexin-43 and its relationship to transforming growth factor β.联合与分离:连接蛋白 43 对 DNA 合成的抑制作用及其与转化生长因子 β 的关系。
Front Pharmacol. 2013 Jul 19;4:90. doi: 10.3389/fphar.2013.00090. eCollection 2013.
6
Connexin and pannexin hemichannels in brain glial cells: properties, pharmacology, and roles.缝隙连接蛋白和 Pannexin 半通道在脑胶质细胞中的特性、药理学和作用。
Front Pharmacol. 2013 Jul 17;4:88. doi: 10.3389/fphar.2013.00088. eCollection 2013.
7
Connexin expression and gap-junctional intercellular communication in ES cells and iPS cells.胚胎干细胞和诱导多能干细胞中的连接蛋白表达和缝隙连接细胞间通讯。
Front Pharmacol. 2013 Jul 3;4:85. doi: 10.3389/fphar.2013.00085. eCollection 2013.
8
The oligodendroglial precursor cell line Oli-neu represents a cell culture system to examine functional expression of the mouse gap junction gene connexin29 (Cx29).少突胶质前体细胞系 Oli-neu 代表了一种细胞培养系统,可用于研究小鼠缝隙连接基因连接蛋白 29(Cx29)的功能表达。
Front Pharmacol. 2013 Jun 28;4:83. doi: 10.3389/fphar.2013.00083. Print 2013.
9
Connexin diversity in the heart: insights from transgenic mouse models.心脏中的连接蛋白多样性:转基因小鼠模型的研究进展。
Front Pharmacol. 2013 Jun 27;4:81. doi: 10.3389/fphar.2013.00081. Print 2013.
10
Regulation of gap junctions by nitric oxide influences the generation of arrhythmias resulting from acute ischemia and reperfusion in vivo.一氧化氮对缝隙连接的调节影响体内急性缺血再灌注引起的心律失常的发生。
Front Pharmacol. 2013 Jun 14;4:76. doi: 10.3389/fphar.2013.00076. eCollection 2013.

Mind the gap! Connexins and pannexins in physiology, pharmacology and disease.

作者信息

Salameh Aida, Blanke Katja, Dhein Stefan

机构信息

Department of Paediatric Cardiology, Heart Centre University of Leipzig Leipzig, Germany.

出版信息

Front Pharmacol. 2013 Nov 21;4:144. doi: 10.3389/fphar.2013.00144. eCollection 2013.

DOI:10.3389/fphar.2013.00144
PMID:24312055
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3836048/
Abstract
摘要