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使用新型抗菌剂进行皮肤感染管理。

Skin infection management using novel antibacterial agents.

作者信息

Mohammadzadeh Ramin, Ahmadiyan Nejla

机构信息

Biotechnology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran. ; Students Research Committee, Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran.

出版信息

Adv Pharm Bull. 2013;3(1):247-8. doi: 10.5681/apb.2013.040. Epub 2013 Feb 7.

Abstract

Pseudomonas aeruginosa and methicillin-resistant Staphylococcus aureus (MRSA) cause difficulties in the management of skin and soft tissue infections and have led to morbidity and mortality in hospital-acquired infections especially in susceptible individuals, those who are generally sick or immunosuppressed. Currently approaches in antibacterial agents offer opportunities to manage the trouble using novel anti-infection systems. Therefore, nanotechnology, a most promising field for generating new applications in medicine, has introduced a most prominent nanoproduct named as nanosilver that revealed excellent antimicrobial activity against some of the hazardous infections. Also cathelicidin peptides which are a part of native immune defense system in the skin and epithelia exhibit excellent antimicrobial activity against some of these perilous infections.

摘要

铜绿假单胞菌和耐甲氧西林金黄色葡萄球菌(MRSA)给皮肤和软组织感染的治疗带来困难,并导致医院获得性感染的发病和死亡,尤其是在易感个体中,即那些通常生病或免疫抑制的人。目前,抗菌药物的方法为使用新型抗感染系统来解决这一问题提供了机会。因此,纳米技术作为医学领域最有前途的新应用领域,推出了一种最突出的纳米产品——纳米银,它对一些危险感染显示出优异的抗菌活性。此外,作为皮肤和上皮组织天然免疫防御系统一部分的cathelicidin肽对其中一些危险感染也表现出优异的抗菌活性。

相似文献

1
Skin infection management using novel antibacterial agents.使用新型抗菌剂进行皮肤感染管理。
Adv Pharm Bull. 2013;3(1):247-8. doi: 10.5681/apb.2013.040. Epub 2013 Feb 7.

本文引用的文献

5
Nanosilver: a nanoproduct in medical application.纳米银:一种应用于医学的纳米产品。
Toxicol Lett. 2008 Jan 4;176(1):1-12. doi: 10.1016/j.toxlet.2007.10.004. Epub 2007 Oct 16.
8
Community-acquired methicillin-resistant Staphylococcus aureus infections.社区获得性耐甲氧西林金黄色葡萄球菌感染
Int J Antimicrob Agents. 2006 Feb;27(2):87-96. doi: 10.1016/j.ijantimicag.2005.11.004. Epub 2006 Jan 19.

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