Deutsch S I, Campbell M
Neuropsychobiology. 1986;15(3-4):160-4. doi: 10.1159/000118260.
In this report, the clinical efficacy of specific neuroleptics in infantile autism was related to the degree to which they bind to different classes of neurotransmitter receptors and calcium channels in brain. Based upon available receptor-binding data, predictions were made regarding the efficacy of neuroleptics which have not yet been studied in this disorder. Future selection of potentially effective agents should be based upon a pharmacological rationale.
在本报告中，特定抗精神病药物治疗婴儿孤独症的临床疗效与它们对大脑中不同类型神经递质受体和钙通道的结合程度有关。根据现有的受体结合数据，对尚未在该疾病中进行研究的抗精神病药物的疗效进行了预测。未来潜在有效药物的选择应基于药理学原理。
