Black J L, Richelson E
Mayo Clin Proc. 1987 May;62(5):369-72. doi: 10.1016/s0025-6196(12)65440-8.
The affinities of antipsychotic agents for neurotransmitter receptors are believed to be responsible for their antipsychotic activity and side-effect profiles. Data on neuroreceptor affinity can be used to predict side-effect profiles of antipsychotic drugs. In this report, we present data on receptor affinity that have been modified to help clinicians clearly see the potential for each drug to produce a specific side effect at any dosage.
抗精神病药物对神经递质受体的亲和力被认为是其抗精神病活性和副作用特征的原因。神经受体亲和力的数据可用于预测抗精神病药物的副作用特征。在本报告中，我们展示了经修改的受体亲和力数据，以帮助临床医生清楚地了解每种药物在任何剂量下产生特定副作用的可能性。
