Oraqix® 对比 Hurricaine® 和安慰剂在非手术牙周治疗中控制疼痛的麻醉效果。
Anesthetic efficacy of Oraqix® versus Hurricaine® and placebo for pain control during non-surgical periodontal treatment.
机构信息
Facultat d'Odontologia (UB), Campus de Bellvitge, Pavelló de Govern, Feixa Llarga, s/n, 08907 L'Hospitalet de Llobregat,
出版信息
Med Oral Patol Oral Cir Bucal. 2014 Mar 1;19(2):e192-201. doi: 10.4317/medoral.19202.
OBJECTIVES
To evaluate the efficacy of Oraqix® during scaling and root planing (SRP) in comparison with 20% benzocaine and placebo.
STUDY DESIGN
15 patients requiring 4 sessions of SRP were enrolled. For each patient, Oraqix®, Hurricaine®, vaseline or no anesthetic product were randomly assigned each to a quadrant. Treatment pain was evaluated on a 100 mm Visual Analog Scale (VAS) and on a Verbal Rating Scale (VRS). The amount of product administered, the need to re-anesthetise, patient and operator satisfaction and the onset of side-effects were also recorded.
RESULTS
Oraqix® was significantly better than nothing, with a reduction of VAS score to 13.3 units, but without significant differences with Vaseline or Hurricaine®. Oraqix® was better in VRS reduction than not using any anesthetic (p=0.001) or using vaseline (p=0.024), but similar to Hurricaine® (p=0.232).
CONCLUSIONS
Oraqix® effectively controls pain in SRP procedures, with few side-effects and a good acceptance on the part of patients and clinicians.
目的
评估 Oraqix® 在牙周洁治（SRP）过程中的疗效，与 20%苯佐卡因和安慰剂进行比较。
研究设计
纳入了 15 名需要进行 4 次 SRP 治疗的患者。对于每位患者，Oraqix®、Hurricaine®、凡士林或无任何麻醉产品随机分配到一个象限。使用 100mm 视觉模拟量表（VAS）和口头评分量表（VRS）评估治疗疼痛。还记录了产品使用量、需要重新麻醉、患者和操作人员满意度以及副作用的发生情况。
结果
Oraqix®明显优于无任何处理，VAS 评分降低了 13.3 个单位，但与凡士林或 Hurricaine®无显著差异。Oraqix®在 VRS 评分降低方面优于不使用任何麻醉剂（p=0.001）或使用凡士林（p=0.024），但与 Hurricaine®相似（p=0.232）。
结论
Oraqix®可有效控制 SRP 过程中的疼痛，副作用少，患者和临床医生接受度良好。
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