Department of Otolaryngology/Head and Neck Surgery, The University of North Carolina at Chapel Hill; Chapel Hill, North Carolina, U.S.A.
Otol Neurotol. 2014 Jan;35(1):64-71. doi: 10.1097/MAO.0000000000000219.
Electrocochleography (ECoG) to acoustic stimuli can differentiate relative degrees of cochlear responsiveness across the population of cochlear implant recipients. The magnitude of the ongoing portion of the ECoG, which includes both hair cell and neural contributions, will correlate with speech outcomes as measured by results on CNC word score tests.
Postoperative speech outcomes with cochlear implants vary from almost no benefit to near normal comprehension. A factor expected to have a high predictive value is the degree of neural survival. However, speech performance with the implant does not correlate with the number and distribution of surviving ganglion cells when measured postmortem. We will investigate whether ECoG can provide an estimate of cochlear function that helps predict postoperative speech outcomes.
An electrode was placed at the round window of the ear about to be implanted during implant surgery. Tone bursts were delivered through an insert earphone. Subjects included children (n = 52, 1-18 yr) and postlingually hearing impaired adults (n = 32). Word scores at 6 months were available from 21 adult subjects.
Significant responses to sound were recorded from almost all subjects (80/84 or 95%). The ECoG magnitudes spanned more than 50 dB in both children and adults. The distributions of ECoG magnitudes and frequencies were similar between children and adults. The correlation between the ECoG magnitude and word score accounted for 47% of the variance.
ECoGs with high signal-to-noise ratios can be recorded from almost all implant candidates, including both adult and pediatric populations. In postlingual adults, the ECoG magnitude is more predictive of implant outcomes than other nonsurgical variables such as duration of deafness or degree of residual hearing.
电 Cochleography（ECoG）对声刺激可以区分耳蜗植入接受者群体中耳蜗反应的相对程度。持续部分的 ECoG 的幅度，包括毛细胞和神经的贡献，将与言语结果相关，以 CNC 单词得分测试的结果来衡量。
耳蜗植入术后的言语结果从几乎没有受益到接近正常的理解。预计具有高预测价值的因素是神经存活的程度。然而，当在死后进行测量时，植入后的言语表现与存活的神经节细胞的数量和分布无关。我们将研究 ECoG 是否可以提供估计耳蜗功能的方法，帮助预测术后言语结果。
在植入手术期间，将电极放置在即将植入的耳朵的圆窗处。通过插入耳机传递音调爆发。受试者包括儿童（n = 52，1-18 岁）和后天听力受损的成年人（n = 32）。21 名成年受试者有 6 个月的单词得分。
几乎所有受试者（80/84 或 95%）都记录到对声音的显著反应。ECoG 幅度在儿童和成年人中都超过 50dB。儿童和成年人之间 ECoG 幅度和频率的分布相似。ECoG 幅度与单词得分之间的相关性解释了 47%的方差。
几乎所有植入候选者，包括成年和儿科人群，都可以记录到具有高信噪比的 ECoG。在后天性聋成年人中，ECoG 幅度比其他非手术变量（如耳聋持续时间或残余听力程度）更能预测植入效果。
