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直肠和乙状结肠癌的症状复发。放射治疗对生活质量的影响。

Symptomatic recurrences of carcinoma of the rectum and sigmoid. The influence of radiotherapy on the quality of life.

作者信息

Pacini P, Cionini L, Pirtoli L, Ciatto S, Tucci E, Sebaste L

出版信息

Dis Colon Rectum. 1986 Dec;29(12):865-8. doi: 10.1007/BF02555365.

DOI:10.1007/BF02555365
PMID:2431843
Abstract

One hundred forty-three patients irradiated for locoregional recurrences after curative surgery for cancer of the rectum and sigmoid were studied retrospectively. An analysis was made of the symptomatic response and survival in the total series and in three subgroups treated with different dose levels (40 Gy or lower, between 40 and 50 Gy, 50 Gy or higher). The symptom-free period was calculated as percent of the overall survival. Symptomatic control was obtained in 80.4 percent of the cases, and the crude patient survival rate was 17.5 percent at two years. No significant difference was found in the three subgroups treated with different dose levels. The cumulative time/patient asymptomatic periods in the total series and in the three subgroups were 31.5, 30.2, 31.8, and 31.9 percent respectively, of the survival period.

摘要

对143例因直肠癌和乙状结肠癌根治性手术后局部区域复发而接受放疗的患者进行了回顾性研究。分析了整个系列以及接受不同剂量水平(40 Gy或更低、40至50 Gy之间、50 Gy或更高)治疗的三个亚组的症状反应和生存率。无症状期计算为总生存期的百分比。80.4%的病例获得了症状控制,两年时患者的粗生存率为17.5%。在接受不同剂量水平治疗的三个亚组中未发现显著差异。整个系列以及三个亚组中每位患者无症状期的累积时间分别为生存期的31.5%、30.2%、31.8%和31.9%。

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