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在喜玛拉雅山脉地区,导致鼻窦炎和鼻息肉的共生糙皮侧耳菌:首例病例报告和综述。

Schizophillum commune causing sinusitis with nasal polyposis in the sub-Himalayan region: first case report and review.

机构信息

Department of Microbiology, Indira Gandhi Medical College, Shimla, Himachal Pradesh, India,

出版信息

Mycopathologia. 2014 Feb;177(1-2):103-10. doi: 10.1007/s11046-013-9717-1. Epub 2013 Dec 7.

Abstract

Schizophillum commune is an environmental fungus rarely causing human infections of diverse nature. Sinusitis occurs in immunocompromised persons and seldom in healthy subjects. Though easily isolated, the lack of awareness of its virulence is a bottleneck in the diagnosis of this infection. We report the first case of S. commune sinusitis with nasal polyps in an immunocompetent male from the sub-Himalayan region. The computerized tomography scan findings established the clinical diagnosis, and causative agent was confirmed as S. commune. A white, woolly mold with septate, hyaline hyphae and characteristic spicules but unclamped connections suggested a monokaryotic isolate. Patient was treated successfully with fiberoptic endoscopic sinus surgery, and no antifungal therapy was instituted. There was no recurrence at review after 1 year.

摘要

commune 是一种环境真菌,很少引起多种性质的人类感染。窦炎发生于免疫功能低下者,很少发生于健康人群。尽管易于分离,但对其毒力的认识不足是诊断这种感染的一个瓶颈。我们报告首例来自喜马拉雅山脉地区的免疫功能正常男性的 S. commune 窦炎伴鼻息肉。计算机断层扫描结果确立了临床诊断,病原体确认为 S. commune。白色、羊毛状的霉菌,有分隔、透明的菌丝和特征性的刺突,但没有未夹紧的连接,提示为单核分离株。患者经纤维内镜鼻窦手术成功治疗,未进行抗真菌治疗。在 1 年的随访中无复发。

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