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1例急性髓细胞白血病患者由裂褶菌和细菌引起的鼻窦炎

A Case of Sinusitis Caused by Schizophyllum Commune and Bacteria in Acute Myelocytic Leukemia.

作者信息

Yin Xiuyun, Liang Yuying, Zeng Lijun, Chen Shuiping

出版信息

Clin Lab. 2015;61(11):1799-801. doi: 10.7754/clin.lab.2015.150418.

Abstract

Schizophyllum commune infections have been rarely reported. Here we reported a rare case of sinusitis in an acute myelocytic leukemia patient, who was co-infected by Escherichia coli, Stenotrophomonas maltophilia, and basidiomycetous fungi (Schizophyllum commune) in sinuses. Considering the in vitro and in vivo anti-fungal activity of voriconazole, it might be a good option to treat Schizophyllum commune infections when antifungal susceptibility testing is not available. When severe side effects occur, amphotericin B or itraconazole might be subsequent choice.

摘要

裂褶菌感染鲜有报道。在此,我们报告了一例急性髓细胞白血病患者的罕见鼻窦炎病例,该患者鼻窦同时感染了大肠杆菌、嗜麦芽窄食单胞菌和担子菌(裂褶菌)。考虑到伏立康唑的体外和体内抗真菌活性,在无法进行抗真菌药敏试验时,它可能是治疗裂褶菌感染的一个不错选择。当出现严重副作用时,两性霉素B或伊曲康唑可能是后续选择。

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