Togashi S, Kobayashi S, Okada M
Dev Biol. 1986 Dec;118(2):352-60. doi: 10.1016/0012-1606(86)90004-7.
Injection of mRNA extracted from Drosophila cleavage embryos or mature oocytes restored pole cell-forming ability to embryos that had been deprived of this ability by uv irradiation. However, mRNA extracted from blastoderms did not show the restoration activity. Pole cells thus formed in uv-irradiated embryos bear similarities to normal pole cells both in their morphology and their ability to migrate to the gonadal rudiments. But this mRNA does not appear to be capable of rescuing uv-induced sterility, or inducing pole cells in the anterior polar region.
注射从果蝇卵裂期胚胎或成熟卵母细胞中提取的mRNA，可使因紫外线照射而丧失极细胞形成能力的胚胎恢复该能力。然而，从囊胚中提取的mRNA并未表现出恢复活性。在紫外线照射的胚胎中如此形成的极细胞，在形态及其迁移至生殖腺原基的能力方面均与正常极细胞相似。但这种mRNA似乎无法挽救紫外线诱导的不育，也无法在前极区诱导极细胞形成。
