Sawada Takahiro, Machino Ryusuke, Ishii Mitsuhisa, Takeji Miyuki, Maeda Toshiharu
Department of Thoracic Surgery, Ehime Prefectural Central Hospital, Matsuyama, Japan.
Kyobu Geka. 2013 Nov;66(12):1105-8.
Mucosa-associated lymphoid tissue (MALT) lymphoma is a rare type of lymphoma that arises in small CD20-positive lymphocytes. We encountered a case of thymic MALT lymphoma treated with surgical intervention during long-term follow-up for Sjögren's syndrome and idiopathic thrombocytopenic purpura (ITP). Although symptomatic remission of Sjögren's syndrome and ITP had already been achieved, the levels of anti-SSA and anti-SSB antibodies remained high. Chronic stimulation by these antibodies may contribute to the development of MALT lymphoma. A careful follow-up may be indicated for this case with a complex immunological background.
黏膜相关淋巴组织（MALT）淋巴瘤是一种罕见的淋巴瘤，由小的CD20阳性淋巴细胞引发。我们遇到一例胸腺MALT淋巴瘤患者，该患者在对干燥综合征和特发性血小板减少性紫癜（ITP）进行长期随访期间接受了手术干预。尽管干燥综合征和ITP已实现症状缓解，但抗SSA和抗SSB抗体水平仍居高不下。这些抗体的慢性刺激可能促使MALT淋巴瘤的发生。对于这例具有复杂免疫背景的病例，可能需要进行密切随访。
