Barrett's Esophagus Unit, Division of Gastroenterology & Hepatology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA.
Nat Rev Gastroenterol Hepatol. 2014 Feb;11(2):82-4. doi: 10.1038/nrgastro.2013.237. Epub 2013 Dec 10.
Advances are being made in understanding the pathogenesis, treatment outcomes and surveillance of Barrett oesophagus. Central obesity and age at onset of gastro-oesophageal reflux are being recognized as risk factors that have implications for screening. The persistent finding of nondysplastic Barrett oesophagus during surveillance is associated with low risk of malignant progression, whereas dysplastic Barrett oesophagus requires continued surveillance.
目前人们对巴雷特食管的发病机制、治疗效果和监测有了更多的了解。人们已经认识到中心性肥胖和胃食管反流病发病年龄是两个与筛查相关的危险因素。在监测过程中持续发现非异型增生性巴雷特食管与恶性进展风险低相关,而异型增生性巴雷特食管则需要持续监测。