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机器人辅助单纯前列腺切除术:系统评价和单机构病例系列报告。

Robotic-assisted simple prostatectomy: a systematic review and report of a single institution case series.

机构信息

San Diego School of Medicine, University of California, La Jolla, CA, USA.

1] San Diego School of Medicine, University of California, La Jolla, CA, USA [2] Department of Urology, University of California San Diego Health System, San Diego, CA, USA.

出版信息

Prostate Cancer Prostatic Dis. 2014 Mar;17(1):1-5. doi: 10.1038/pcan.2013.52. Epub 2013 Dec 10.

Abstract

Open simple prostatectomy (OSP) is an effective treatment for patients with symptomatic BPH and larger volume prostates; however, it is associated with substantial risks of bleeding, transfusion and prolonged hospital length of stay (LOS). Robotic-assisted simple prostatectomy (RASP) potentially offers improved perioperative outcomes for these patients. We systematically reviewed published data on RASP outcomes and analyzed our experience at the University of California San Diego (UCSD). We identified eight published studies, all non-comparative case series (Level 3 evidence), reporting a total of 109 RASP cases from 2008 to 2012. Indications included acute urinary retention (n=48), persistent obstructive symptoms (n=51), failure of medical management (n=9) and recurrent urinary tract infections (n=2). The mean ages ranged from 65 to 77 years. More than 75% of the studies reported a mean LOS <3 days and a transfusion prevalence of 0%. The mean resected prostate weights ranged from 51 to 301 g. For UCSD, indications for surgery included urinary retention (n=11) and failure of medical management (n=5). The mean age was 68 years, transfusion prevalence 0%, mean resected prostate weight 94 g and mean LOS 1 day. All nine series observed substantial postoperative improvements in urinary symptoms and retention. These data suggest that RASP is a safe and efficacious treatment for BPH in select patients with larger prostates. Although LOS and transfusion prevalence for RASP are markedly lower than the published OSP series, comparative studies are needed to verify these results.

摘要

开放式单纯前列腺切除术(OSP)是治疗有症状的 BPH 和较大体积前列腺的有效方法;然而,它与大量出血、输血和延长住院时间(LOS)的风险相关。机器人辅助单纯前列腺切除术(RASP)可能为这些患者提供更好的围手术期结果。我们系统地回顾了已发表的关于 RASP 结果的数据,并分析了我们在加利福尼亚大学圣地亚哥分校(UCSD)的经验。我们确定了八项已发表的研究,均为非对照病例系列(3 级证据),报告了 2008 年至 2012 年共 109 例 RASP 病例。适应证包括急性尿潴留(n=48)、持续梗阻症状(n=51)、药物治疗失败(n=9)和复发性尿路感染(n=2)。平均年龄范围为 65 至 77 岁。超过 75%的研究报告平均 LOS<3 天,输血率为 0%。平均切除前列腺重量范围为 51 至 301g。对于 UCSD,手术适应证包括尿潴留(n=11)和药物治疗失败(n=5)。平均年龄为 68 岁,输血率为 0%,平均切除前列腺重量为 94g,平均 LOS 为 1 天。所有 9 个系列都观察到术后尿症状和保留方面有显著改善。这些数据表明,RASP 是一种安全有效的治疗方法,适用于选择的前列腺较大的 BPH 患者。尽管 RASP 的 LOS 和输血率明显低于已发表的 OSP 系列,但需要进行比较研究来验证这些结果。

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