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机器人辅助单纯前列腺切除术与钬激光剜除术治疗大体积良性前列腺增生:韩国一项单中心初步研究

Robotic-assisted simple prostatectomy versus holmium laser enucleation of the prostate for large benign prostatic hyperplasia: A single-center preliminary study in Korea.

作者信息

Kim Byung Hoon, Byun Hye Jin

机构信息

Department of Urology, Keimyung University School of Medicine, Dongsan Hospital, Daegu, Korea.

出版信息

Prostate Int. 2022 Sep;10(3):123-128. doi: 10.1016/j.prnil.2022.05.004. Epub 2022 May 29.

Abstract

BACKGROUND

Holmium laser enucleation of the prostate (HoLEP) and robotic-assisted simple prostatectomy (RASP) are the two most important therapeutic modalities for large benign prostatic hyperplasia. However, there are currently no studies comparing these two treatments in a Korean setting. In this study, the authors seek to compare the safety and efficacy associated with these procedures.

METHODS

The authors retrospectively analyzed 59 male patients who underwent HoLEP (n = 26) or RASP (n = 33) at single center. The following preoperative data were compared: age, the International Prostatic Symptom Score (IPSS), transrectal ultrasonography, uroflowmetry, and hemoglobin. Intraoperative data included operation time and specimen weight. Postoperative data included change in IPSS, uroflowmetry, and hemoglobin. Length of stay, catheterization time, and complications were also reviewed.

RESULTS

No significant differences between the two groups were found in terms of age, total prostate, and transitional volume. Postoperatively, both groups showed similar improvement in the maximum flow rate, post-void residual urine, IPSS, and quality of life. Intraoperatively, there were no differences regarding operation time and resected prostate volume. Catheter removal time and length of stay were significantly shorter in the HoLEP group than the RASP group. In addition, postoperative hemoglobin changes were significantly lower in the HoLEP group. However, incontinence rates at 1 month and 2 months postoperative in the RASP group were lower than the HoLEP group.

CONCLUSIONS

Both HoLEP and RASP can produce excellent postoperative outcomes. However, catheter removal time, length of stay, and hemoglobin changes were more favorable in the HoLEP group. On the other hand, postoperative incontinence was more favorable in the RASP group. These factors must be heavily considered when deciding surgical the method for large benign prostatic hyperplasia.

摘要

背景

钬激光前列腺剜除术(HoLEP)和机器人辅助单纯前列腺切除术(RASP)是治疗大型良性前列腺增生的两种最重要的治疗方式。然而,目前在韩国背景下尚无比较这两种治疗方法的研究。在本研究中,作者旨在比较与这些手术相关的安全性和有效性。

方法

作者回顾性分析了在单一中心接受HoLEP(n = 26)或RASP(n = 33)的59例男性患者。比较了以下术前数据:年龄、国际前列腺症状评分(IPSS)、经直肠超声检查、尿流率和血红蛋白。术中数据包括手术时间和标本重量。术后数据包括IPSS、尿流率和血红蛋白的变化。还回顾了住院时间、导尿时间和并发症。

结果

两组在年龄、前列腺总体积和移行区体积方面无显著差异。术后,两组在最大尿流率、排尿后残余尿量、IPSS和生活质量方面均有相似的改善。术中,手术时间和切除的前列腺体积无差异。HoLEP组的拔管时间和住院时间明显短于RASP组。此外,HoLEP组术后血红蛋白变化明显更低。然而,RASP组术后1个月和2个月时的尿失禁发生率低于HoLEP组。

结论

HoLEP和RASP均可产生优异的术后效果。然而,HoLEP组的拔管时间、住院时间和血红蛋白变化更有利。另一方面,RASP组术后尿失禁情况更有利。在决定大型良性前列腺增生的手术方法时,必须充分考虑这些因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/798c/9520426/2d22c400ae0e/gr1.jpg

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