Massachusetts General Hospital, Radiation Oncology, 100 Blossom Street, Boston, MA, 02114, USA.
Curr Oncol Rep. 2014;16(1):362. doi: 10.1007/s11912-013-0362-0.
The role and sequencing of radiotherapy in the management of T3-4 or node-positive rectal cancer has evolved over the last few decades. Given the significant local failure rate following surgery alone, both preoperative and postoperative chemotherapy and radiotherapy have been studied to decrease local and systemic failure and improve survival in these patients. This review discusses current indications and controversies for treatment of stage II-III rectal cancer patients.
在过去几十年中，放疗在 T3-4 或淋巴结阳性直肠癌治疗中的作用和顺序发生了变化。鉴于单纯手术治疗后局部复发率较高，术前和术后化疗和放疗均已被研究用于降低局部和全身失败率，并改善这些患者的生存。本文讨论了目前治疗 II-III 期直肠癌患者的适应证和争议。
