Wan Xuejuan, Liu Haiyang, Yao Shen, Liu Tianqi, Yao Youwei
College of Materials Science and Engineering, Shenzhen University, Shenzhen, 518060, China; Institute of Advanced Materials, Graduate School at Shenzhen, Tsinghua University, Shenzhen, 518055, China; Key Laboratory for Advanced Materials of Ministry of Education, Department of Materials Science and Engineering, Tsinghua University, Beijing, 100084, China.
Macromol Rapid Commun. 2014 Feb;35(3):323-9. doi: 10.1002/marc.201300810. Epub 2013 Dec 9.
Stimuli-responsive poly(N-isopropylacrylamide) nanogel with covalently labeled rhodamine B urea derivatives (P(NIPAM-co-RhBUA)) is utilized as a sensitive fluorescent probe for Cr(3+) in aqueous solution, and its thermo-induced tunable detection capacity is investigated. At 20 °C, non-fluorescent nanogel can selectively bind with Cr(3+) over some other metal ions, leading to prominent fluorescence OFF-ON switching due to the recognition of RhBUA with Cr(3+) . Upon heating above the phase transition temperature, enhanced fluorescence intensity is observed (≈61-fold increase at 45 °C) for the nanogel in the presence of Cr(3+) , accompanied with an improved detection sensitivity, which suggest that hydrophobic microenvironment generated in the collapsed nanogel plays an active role for their detection performance.
具有共价标记罗丹明B尿素衍生物的刺激响应性聚（N-异丙基丙烯酰胺）纳米凝胶（P（NIPAM-co-RhBUA））被用作水溶液中Cr(3+)的灵敏荧光探针，并研究了其热诱导可调检测能力。在20℃时，非荧光纳米凝胶可以比其他一些金属离子更选择性地与Cr(3+)结合，由于RhBUA与Cr(3+)的识别导致显著的荧光开-关切换。在加热到相变温度以上时，在Cr(3+)存在下观察到纳米凝胶的荧光强度增强（45℃时约增加61倍），同时检测灵敏度提高，这表明在塌陷的纳米凝胶中产生的疏水微环境对其检测性能起到了积极作用。
