INSTM and Chemistry for Technologies Lab, University of Brescia, via Branze 38, 25123, Brescia, ITALY.
Small. 2014 Apr 9;10(7):1294-8. doi: 10.1002/smll.201303166. Epub 2013 Dec 9.
Core-shell colloidal crystals can act as very efficient traps for light and analytes. Here it is shown that Raman-active probes can be achieved using SiO2-TiO2 core-shell beads. These systems are successfully tested in monitoring of glutathione redox cycle at physiological concentration in aqueous environment, without need of any interfering enhancers. These materials represent a promising alternative to conventional, metal-based SERS probes for investigating chemical and biochemical reactions under real working conditions.
核壳胶体晶体可以作为光和分析物的非常有效的陷阱。本文表明，可以使用 SiO2-TiO2 核壳珠来实现拉曼活性探针。这些系统在生理浓度的水溶液环境中成功地用于监测谷胱甘肽氧化还原循环，而无需任何干扰增强剂。这些材料代表了传统基于金属的 SERS 探针的有前途的替代品，可用于在实际工作条件下研究化学和生物化学反应。
