Institute of Chinese Medicine, The Chinese University of Hong Kong, Hong Kong ; State Key Laboratory of Phytochemistry and Plant Resources in West China, The Chinese University of Hong Kong, Hong Kong.
Evid Based Complement Alternat Med. 2013;2013:319703. doi: 10.1155/2013/319703. Epub 2013 Nov 12.
Objective. Mortality arising from cardiovascular pathologies remains one of the highest. Maintenance of cardiovascular health therefore remains a universal concern. Interventional therapies and medications have made impressive advances, but preventive measures would be of the same importance. Method. Ten years' search for a simple herbal formula has resulted in a two-herb combination, consisting of Salviae Miltiorrhizae Radix et Rhizoma and Puerariae Lobatae Radix. The formula has been studied extensively on cardiovascular biological platforms and then put on three clinical trials. Results. In the laboratory, the formula was found to have the biological effects of anti-inflammation, anti-oxidation, anti-foam cell formation on vascular endothelium, and vasodilation. Clinical trials using ultrasonic carotid intima thickness as a surrogate marker showed very significant benefits. No significant adverse effects were encountered. Conclusion. It is therefore recommended that the herbal formula could be used as an adjuvant therapy in cardiac patients under treatment or as a preventive agent among the susceptible.
心血管疾病导致的死亡率仍然居高不下。因此，维护心血管健康仍是全球关注的重点。介入治疗和药物治疗已经取得了令人瞩目的进展，但预防措施同样重要。
经过十年的寻找，我们发现了一种简单的草药配方，由丹参和葛根组成。该配方已在心血管生物学平台上进行了广泛研究，并进行了三项临床试验。
在实验室中，该配方具有抗炎、抗氧化、抗血管内皮泡沫细胞形成和血管扩张的生物学作用。使用超声颈动脉内膜中层厚度作为替代标志物的临床试验显示出非常显著的益处。未发现明显的不良反应。
因此，建议该草药配方可作为治疗心脏病患者的辅助治疗药物，或作为易感人群的预防药物。
