Eldar M, Griffin J C, Seger J J, Abbott J A, Ruder M A, Davis J C, Herre J M, Scheinman M M
Pacing Clin Electrophysiol. 1986 Nov;9(6):810-20. doi: 10.1111/j.1540-8159.1986.tb06630.x.
Seven patients with accessory pathway and symptomatic atrioventricular reciprocating tachycardia underwent catheter ablation of the atrioventricular junction (AVJ). Four patients had the Wolff-Parkinson-White syndrome, two had concealed left free-wall accessory pathways, and one patient had a nodoventricular connection. All patients failed multiple antiarrhythmic drugs and one failed attempted surgical ablation of a posteroseptal accessory pathway. Chronic interruption of atrioventricular node-His conduction was achieved in all patients. Over a mean follow-up period of 21 +/- 14 months, four patients remained asymptomatic without antiarrhythmic therapy. One patient developed atrial fibrillation after magnet application to her VVI pacemaker, another developed atrial flutter, and a third had nonparoxysmal sinus or atrial tachycardia. Two patients required chronic quinidine therapy. Two patients with concealed accessory pathways had pacemaker-mediated tachycardia which was controlled by pacemaker reprogramming. Atrioventricular junctional ablation in patients with accessory pathways proved effective in that all are currently controlled without need for surgical intervention. On follow-up, a relatively high incidence of atrial arrhythmias requiring antiarrhythmic therapy was found.
7例有旁路且有症状性房室折返性心动过速的患者接受了房室交界区(AVJ)导管消融术。4例患者患有预激综合征,2例有隐匿性左游离壁旁路,1例患者有结室连接。所有患者多种抗心律失常药物治疗无效,1例患者后间隔旁路手术消融尝试失败。所有患者均实现了房室结 - 希氏束传导的慢性阻断。在平均21±14个月的随访期内,4例患者在未接受抗心律失常治疗的情况下仍无症状。1例患者在其VVI起搏器应用磁铁后发生房颤,另1例发生房扑,第3例出现非阵发性窦性或房性心动过速。2例患者需要长期服用奎尼丁治疗。2例有隐匿性旁路的患者出现起搏器介导的心动过速,通过起搏器重新编程得以控制。有旁路的患者进行房室交界区消融术证明是有效的,因为目前所有患者均得到控制,无需手术干预。随访发现,需要抗心律失常治疗的房性心律失常发生率相对较高。