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与丙戊酸钠相关的银屑病样药疹。

Psoriasiform drug eruption associated with sodium valproate.

作者信息

Gul Mert Gulen, Incecik Faruk, Gunasti Suhan, Herguner Ozlem, Altunbasak Sakir

机构信息

Division of Pediatric Neurology, Department of Pediatrics, Cukurova University, 01180 Adana, Turkey.

出版信息

Case Rep Pediatr. 2013;2013:823469. doi: 10.1155/2013/823469. Epub 2013 Nov 13.

DOI:10.1155/2013/823469
PMID:24324909
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3845398/
Abstract

As psoriasis is a common skin disorder, knowledge of the factors that may induce, trigger, or exacerbate the disease is of primary importance in clinical practice. Drug intake is a major concern in this respect, as new drugs are constantly being added to the list of factors that may influence the course of the disease. We report a patient with a psoriasiform drug eruption associated with the use of sodium valproate. Physicians should be aware of this type of reaction. Early detection of these cases has practical importance since the identification and elimination of the causative drug are essential for therapy success.

摘要

由于银屑病是一种常见的皮肤疾病,了解可能诱发、引发或加重该病的因素在临床实践中至关重要。在这方面,药物摄入是一个主要问题,因为可能影响疾病进程的因素清单中不断增加新的药物。我们报告一例与使用丙戊酸钠相关的银屑病样药疹患者。医生应意识到这种类型的反应。早期发现这些病例具有实际意义,因为识别和停用致病药物是治疗成功的关键。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1e18/3845398/59e3745378b2/CRIM.PEDIATRICS2013-823469.005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1e18/3845398/357e01f11eb1/CRIM.PEDIATRICS2013-823469.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1e18/3845398/33dbe9ca4cd7/CRIM.PEDIATRICS2013-823469.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1e18/3845398/4182f9335233/CRIM.PEDIATRICS2013-823469.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1e18/3845398/936cef849442/CRIM.PEDIATRICS2013-823469.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1e18/3845398/59e3745378b2/CRIM.PEDIATRICS2013-823469.005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1e18/3845398/357e01f11eb1/CRIM.PEDIATRICS2013-823469.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1e18/3845398/33dbe9ca4cd7/CRIM.PEDIATRICS2013-823469.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1e18/3845398/4182f9335233/CRIM.PEDIATRICS2013-823469.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1e18/3845398/936cef849442/CRIM.PEDIATRICS2013-823469.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1e18/3845398/59e3745378b2/CRIM.PEDIATRICS2013-823469.005.jpg

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本文引用的文献

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Drug induced psoriasis.药物性银屑病
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Dose-related levetiracetam-induced reticulated drug eruption.与剂量相关的左乙拉西坦诱发的网状药疹。
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Drug-induced psoriasis. Recognition and management.药物性银屑病。识别与管理。
Am J Clin Dermatol. 2000 May-Jun;1(3):159-65. doi: 10.2165/00128071-200001030-00003.
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Psoriasiform eruption and anticonvulsant drugs.
Acta Derm Venereol. 2000 Sep-Oct;80(5):382.
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Psoriasiform eruption induced by anticonvulsants.
Isr J Med Sci. 1994 Apr;30(4):283-6.
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Hemorrhagic pancreatitis in a young child following valproic acid therapy. Clinical and ultrasonic assessment.一名幼儿在接受丙戊酸治疗后发生出血性胰腺炎。临床及超声评估。
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