Dell'Osa D, Temple D M
Pharmacol Res Commun. 1986 Nov;18(11):1043-52. doi: 10.1016/0031-6989(86)90021-4.
Verapamil, a calcium channel blocker, significantly inhibited the release of slow-reacting substance of anaphylaxis (SRS-A) from cat lung fragments challenged with either the calcium ionophore, A23187, or Ascaris extract. This effect was observed when verapamil was present at the concentrations of 10 microM and 50 microM. Chlorpromazine 10 microM significantly inhibited antigen-induced SRS-A release. Histamine release was low and no significant effect by verapamil or chlorpromazine could be shown.
维拉帕米，一种钙通道阻滞剂，可显著抑制在用钙离子载体A23187或蛔虫提取物刺激的猫肺组织碎片中过敏反应慢反应物质（SRS-A）的释放。当维拉帕米浓度为10微摩尔和50微摩尔时可观察到这种效应。10微摩尔的氯丙嗪可显著抑制抗原诱导的SRS-A释放。组胺释放量较低，未显示维拉帕米或氯丙嗪有显著作用。
