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坏死性筋膜炎

Necrotising fasciitis.

作者信息

Dapunt Ulrike, Klingmann Alexander, Schmidmaier Gerhard, Moghaddam Arash

机构信息

Department of Orthopaedics and Trauma Surgery, Heidelberg University, Heidelberg, Germany.

出版信息

BMJ Case Rep. 2013 Dec 10;2013:bcr2013201906. doi: 10.1136/bcr-2013-201906.

DOI:10.1136/bcr-2013-201906
PMID:24326439
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3863064/
Abstract

A patient in his late 50s who suffered from necrotising fasciitis is described in this case report. The patient first presented at the chest pain unit, where he reported of respiratory distress and showed systemic signs of an infection. Because of progressive skin lesions indicative of necrotising fasciitis on both the lower extremities, the patient was immediately rushed into surgery and was treated at the intensive care unit. Despite receiving immediate treatment, the patient died of this rapidly spreading infectious disease. Because of the fast advance of this disease, we would like to emphasise the importance of early recognition of symptoms.

摘要

本病例报告描述了一名50多岁患有坏死性筋膜炎的患者。该患者最初在胸痛科就诊,自述有呼吸窘迫症状,并表现出感染的全身症状。由于双下肢出现提示坏死性筋膜炎的进行性皮肤病变,患者立即被紧急送往手术室,并在重症监护病房接受治疗。尽管接受了及时治疗,患者仍死于这种迅速传播的传染病。鉴于这种疾病进展迅速,我们想强调早期识别症状的重要性。

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本文引用的文献

1
A case of necrotizing fasciitis with a LRINEC score of zero: clinical suspicion should trump scoring systems.一例实验室坏死性筋膜炎严重程度评分(LRINEC)为零的坏死性筋膜炎病例:临床怀疑应胜过评分系统。
J Emerg Med. 2013 May;44(5):928-31. doi: 10.1016/j.jemermed.2012.09.039. Epub 2012 Dec 31.
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Molecular pathogenesis of necrotizing fasciitis.坏死性筋膜炎的分子发病机制。
Annu Rev Pathol. 2010;5:1-31. doi: 10.1146/annurev-pathol-121808-102135.
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Necrotising fasciitis of upper and lower limb: a systematic review.上肢和下肢坏死性筋膜炎:一项系统评价
Injury. 2007 Dec;38 Suppl 5:S19-26. doi: 10.1016/j.injury.2007.10.030. Epub 2007 Nov 28.
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Blunt trauma as a risk factor for group A streptococcal necrotizing fasciitis.钝性创伤作为A组链球菌坏死性筋膜炎的一个危险因素。
Ann Epidemiol. 2007 Nov;17(11):878-81. doi: 10.1016/j.annepidem.2007.05.011. Epub 2007 Aug 13.
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Necrotizing soft-tissue infection: diagnosis and management.坏死性软组织感染:诊断与管理
Clin Infect Dis. 2007 Mar 1;44(5):705-10. doi: 10.1086/511638. Epub 2007 Jan 22.
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Group A streptococcal myonecrosis: increased vimentin expression after skeletal-muscle injury mediates the binding of Streptococcus pyogenes.A组链球菌性肌坏死:骨骼肌损伤后波形蛋白表达增加介导化脓性链球菌的黏附。
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Curr Opin Infect Dis. 2005 Apr;18(2):101-6. doi: 10.1097/01.qco.0000160896.74492.ea.
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The LRINEC (Laboratory Risk Indicator for Necrotizing Fasciitis) score: a tool for distinguishing necrotizing fasciitis from other soft tissue infections.LRINEC(坏死性筋膜炎实验室风险指标)评分:一种区分坏死性筋膜炎与其他软组织感染的工具。
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