Marques Sílvio Alencar, Abbade Luciana Patrícia Fernandes
Faculdade de Medicina, Universidade Estadual Paulista, Botucatu, SP, Brazil.
Faculdade de Medicina, Universidade Estadual Paulista, Botucatu, SP, Brazil.
An Bras Dermatol. 2020 Jul-Aug;95(4):407-417. doi: 10.1016/j.abd.2020.04.003. Epub 2020 May 16.
The severe bacterial diseases discussed herein are those that present dermatological lesions as their initial manifestations, for which the dermatologist is often called upon to give an opinion or is even the first to examine the patient. This review focuses on those that evolve with skin necrosis during their natural history, that is, necrotizing fasciitis, Fournier gangrene, and ecthyma gangrenosum. Notice that the more descriptive terminology was adopted; each disease was individualized, rather than being referred by the generic term "necrotizing soft tissue infections". Due to their relevance and increasing frequency, infections by methicillin-resistant Staphylococcus aureus (MRSA) were also included, more specifically abscesses, furuncle, and carbuncle, and their potential etiologies by MRSA. This article focuses on the epidemiology, clinical dermatological manifestations, methods of diagnosis, and treatment of each of the diseases mentioned.
本文所讨论的严重细菌性疾病是那些以皮肤病变为初始表现的疾病,皮肤科医生常被要求对此发表意见,甚至是第一个检查患者的医生。本综述重点关注那些在自然病程中伴有皮肤坏死演变的疾病,即坏死性筋膜炎、福尼尔坏疽和坏疽性脓皮病。请注意采用了更具描述性的术语;每种疾病都被个体化描述,而不是用通用术语“坏死性软组织感染”来指代。由于耐甲氧西林金黄色葡萄球菌(MRSA)感染的相关性和发病率不断增加,也将其纳入其中,更具体地说是脓肿、疖和痈,以及由MRSA引起的潜在病因。本文重点关注上述每种疾病的流行病学、临床皮肤表现、诊断方法和治疗。