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人乳腺癌中雌激素受体的测定:酶免疫测定法与葡聚糖包被活性炭法的比较

Determination of estrogen receptors in human breast cancer: comparison between enzyme immunoassay and dextran-coated charcoal method.

作者信息

Bozzetti C, Naldi N, Guazzi A, Nizzoli R, Benecchi M, Cocconi G

出版信息

Tumori. 1986 Oct 31;72(5):511-4. doi: 10.1177/030089168607200511.

DOI:10.1177/030089168607200511
PMID:2432712
Abstract

Estrogen receptor determination was performed on 120 breast cancer cytosols, using the dextran-coated charcoal method (DCC) and an enzyme immunoassay (EIA) to compare the efficiency of the two techniques. A strong correlation was noted between ER concentrations determined by DCC and EIA (P less than 0.001). The mean ER-EIA value was significantly higher than the mean ER-DCC value in premenopausal (P less than 0.001) as well in postmenopausal (P less than 0.001) patients.

摘要

采用葡聚糖包被活性炭法(DCC)和酶免疫测定法(EIA)对120份乳腺癌细胞溶质进行雌激素受体测定,以比较这两种技术的效率。结果发现,DCC法和EIA法测定的雌激素受体(ER)浓度之间存在很强的相关性(P<0.001)。绝经前患者(P<0.001)和绝经后患者(P<0.001)中,ER-EIA的平均数值均显著高于ER-DCC的平均数值。

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Tumori. 1986 Oct 31;72(5):511-4. doi: 10.1177/030089168607200511.
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