马来酸酐共聚物的干扰素诱导及抗病毒活性
[Interferon-inducing and antiviral activity of maleic anhydride copolymers].
作者信息
Nosik N N, Ershov F I, Kozlovskiĭ M M, Vinograd I A, Krentsel' B A
出版信息
Vopr Virusol. 1986 Sep-Oct;31(5):605-9.
PMID:2432730
Abstract
Data on synthesis of new polymer compounds with potential interferon-inducing and antiviral activity are presented. Maleic anhydride (MA)-based alternating copolymers, in particular, copolymers of divinyl ether with MA containing five-member oxygen cycles in the chain, as well as furan copolymers with MA, were shown to be promising interferon inducers. The antiviral activity was found in copolymers based on allene hydrocarbons.
摘要
本文介绍了具有潜在干扰素诱导和抗病毒活性的新型高分子化合物的合成数据。特别是基于马来酸酐（MA）的交替共聚物，即链中含有五元氧环的二乙烯基醚与MA的共聚物，以及呋喃与MA的共聚物，被证明是有前景的干扰素诱导剂。在基于丙二烯烃的共聚物中发现了抗病毒活性。
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