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单纯性经血管栓塞治疗骶骨动脉瘤样骨囊肿。

Serial endovascular embolization as stand-alone treatment of a sacral aneurysmal bone cyst.

机构信息

Departments of Neurology and.

出版信息

J Neurosurg Spine. 2014 Feb;20(2):234-8. doi: 10.3171/2013.11.SPINE13412. Epub 2013 Dec 13.

Abstract

Aneurysmal bone cysts (ABCs) are destructive cystic lesions of the bone and are common in children. They are expansile in nature and, therefore, may become symptomatic. These have traditionally been treated surgically; but recently, endovascular embolization has shown promise as a stand-alone therapy. The authors describe a case of an ABC highlighting the effectiveness and efficiency of endovascular treatment. A 16-year-old boy was referred for a 4-month history of radiating back pain and urinary hesitancy. Findings from his neurological examination were normal, but he had problems ambulating because of pain. Magnetic resonance imaging and CT scanning showed a cystic mass in the sacrum; a biopsy was performed and diagnosis of ABC was confirmed. Treatment options were then discussed with the family. The patient underwent 2 endovascular embolizations in approximately 1 month: Onyx 18 was involved in the first session, and N-butyl cyanoacrylate glue was used in the second session. After the first treatment, the patient experienced a dramatic decrease in pain and concomitant improvement in function. The patient went from being mildly symptomatic after the first treatment to completely asymptomatic after the second treatment. Clinical and radiographic follow-up obtained at 2, 6, and 18 months after initial treatment revealed the patient to be asymptomatic with progressive ossification. Endovascular treatment can be effective in treating symptomatic cases of ABC in which surgery would carry significant risk. Selective arterial embolization can promote sclerosis and result in an immediate and significant decrease in pain.

摘要

动脉瘤样骨囊肿(ABC)是一种常见于儿童的破坏性囊性骨病变。它们具有扩张性,因此可能会出现症状。这些病变传统上通过手术治疗;但最近,血管内栓塞已显示出作为一种独立治疗方法的潜力。作者描述了一个 ABC 病例,突出了血管内治疗的有效性和效率。一名 16 岁男孩因 4 个月的放射性背痛和尿犹豫而被转诊。他的神经系统检查结果正常,但由于疼痛而难以行走。磁共振成像和 CT 扫描显示骶骨有囊性肿块;进行了活检,确诊为 ABC。然后与家人讨论了治疗方案。患者在大约 1 个月内接受了 2 次血管内栓塞:第一次使用了 Onyx 18,第二次使用了 N-丁基氰基丙烯酸酯胶。第一次治疗后,患者的疼痛明显减轻,功能同时得到改善。第一次治疗后,患者从轻度症状变为完全无症状。在初始治疗后 2、6 和 18 个月进行的临床和放射学随访显示,患者无症状,且骨化逐渐进展。血管内治疗对手术风险较大的有症状 ABC 病例可能有效。选择性动脉栓塞可促进硬化,并立即显著减轻疼痛。

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