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一名早产儿暴发性阴沟肠杆菌败血症并发华-佛综合征:糖皮质激素的未决问题

Waterhouse Friderichsen syndrome complicating fulminant Enterobacter cloacae sepsis in a preterm infant: the unresolved issue of corticosteroids.

作者信息

Pode-Shakked Ben, Sadeh-Vered Tal, Kidron Dvora, Kuint Jacob, Strauss Tzipora, Leibovitch Leah

机构信息

1 Department of Neonatology, Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Tel HaShomer, Israel.

出版信息

Fetal Pediatr Pathol. 2014 Apr;33(2):104-8. doi: 10.3109/15513815.2013.864350. Epub 2013 Dec 13.

Abstract

Bilateral adrenal hemorrhage can complicate severe sepsis in the neonate and is most commonly attributed to meningococcal disease; however, it can be caused by other etiologic agents as well. We report herein a fatal case of Enterobacter cloacae sepsis in a preterm infant, resulting in massive adrenal hemorrhages. This is the first documented case of adrenal hemorrhage following infection with this pathogen.

摘要

双侧肾上腺出血可使新生儿严重脓毒症复杂化,最常见的病因是脑膜炎球菌病;然而,它也可由其他病原体引起。我们在此报告一例早产儿阴沟肠杆菌脓毒症致死病例,该病例导致了大量肾上腺出血。这是首例记录在案的由该病原体感染引发肾上腺出血的病例。

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