Chapman C E, Fairweather D S, Keeling A A, Chandler S T, Dykes P W, Bradwell A R
Br J Radiol. 1986 Dec;59(708):1175-8. doi: 10.1259/0007-1285-59-708-1175.
Anti-alpha-fetoprotein (AFP) radioimmunodetection was performed in response to clinical requests in 16 patients. In two patients, assessment of a known tumour was required; the anti-AFP scans were accurate and provided useful clinical information in both cases. In the remaining 14 patients the request was for localisation of suspected recurrent tumour. Accurate information was provided in four of these patients. In this latter group, various conventional methods of investigation had failed to disclose the site of recurrence. However, of a total of 21 sites reported as positive in these 14 patients, eight proved to be false positives. Two false negative results also occurred in this group and nine could not be evaluated. Although occasionally patients were usefully scanned, improvements are necessary before consistently reliable information can be obtained using this technique.
应临床需求，对16例患者进行了抗甲胎蛋白（AFP）放射免疫检测。其中2例患者需要评估已知肿瘤；抗AFP扫描结果准确，在这两个病例中均提供了有用的临床信息。其余14例患者的检测需求是定位疑似复发性肿瘤。这组患者中有4例获得了准确信息。在这后一组患者中，各种传统检查方法均未能发现复发部位。然而，在这14例患者报告为阳性的总共21个部位中，有8个被证明为假阳性。该组中还出现了2例假阴性结果，9个部位无法评估。尽管偶尔能对患者进行有效的扫描，但在使用该技术获得始终可靠的信息之前，仍有必要进行改进。
