Weill Cornell Medical College and Memorial Sloan-Kettering Cancer Center, New York NY.
Duke Cancer Institute, Durham, NC.
Semin Oncol. 2013 Dec;40(6):745-56. doi: 10.1053/j.seminoncol.2013.09.011.
Unfavorable physiological, biological, and behavioral alterations during and following treatment for cancer may lead to chronic energy imbalance predisposing to a myriad of deleterious health conditions including obesity, dyslipidemia, and the metabolic syndrome. In addition to the cardiovascular and musculoskeletal effects of these conditions, energy imbalance and metabolic changes after cancer treatment can also affect cancer-related morbidity and mortality. To this end, lifestyle interventions such as diet and physical activity are especially relevant to mitigate the deleterious impact of chronic energy imbalance in cancer survivors.
癌症治疗期间和之后出现的不利生理、生物和行为改变可能导致慢性能量失衡,从而导致多种有害健康状况,包括肥胖、血脂异常和代谢综合征。除了这些疾病对心血管和肌肉骨骼的影响外,癌症治疗后能量失衡和代谢变化也会影响癌症相关发病率和死亡率。为此,饮食和体育活动等生活方式干预措施对于减轻癌症幸存者慢性能量失衡的有害影响尤为重要。