儿童青少年特发性关节炎的口腔和唾液临床参数。

Clinical oral and salivary parameters of children with juvenile idiopathic arthritis.

机构信息

Centro Universitário de Volta Redonda (UniFoa), Volta Redonda, Rio de Janeiro, Brazil.

Universidade Cruzeiro do Sul, São Paulo, São Paulo, Brazil.

出版信息

Oral Surg Oral Med Oral Pathol Oral Radiol. 2014 Jan;117(1):75-80. doi: 10.1016/j.oooo.2013.08.024.

DOI:10.1016/j.oooo.2013.08.024

PMID:24332330

Abstract

OBJECTIVE

To evaluate clinical oral and salivary parameters of individuals with juvenile idiopathic arthritis (JIA).

STUDY DESIGN

Clinical parameters and whole saliva were collected from children aged 6 to 12 years with JIA (n = 36) and from a healthy, matched control group (n = 36). The clinical and salivary parameters evaluated were the dental caries (decayed, missing, or filled teeth), gingival and simplified oral hygiene indices, salivary flow rate, pH, buffer capacity, total protein, and secretory immunoglobulin A concentrations.

RESULTS

JIA individuals presented poorer oral hygiene (P ≤ .05) but no difference in the dental caries and gingival indices. JIA patients presented an increase in total protein concentration (86%) and buffer capacity in the range of pH 6.9 to 6.0 (10%) and a reduction in initial pH (6%), buffer capacity in the range of pH ≥ 7.0 (50%), and immunoglobulin A concentration (27%) (P ≤ .05).

CONCLUSIONS

JIA is associated with poor oral hygiene and salivary changes, including reductions in immune factors and an altered profile of salivary buffer capacity.

摘要

目的

评估幼年特发性关节炎（JIA）患者的口腔临床和唾液参数。

研究设计

从 6 至 12 岁患有 JIA（n = 36）的儿童和健康的匹配对照组（n = 36）中收集临床参数和全唾液。评估的临床和唾液参数包括龋齿（龋齿、缺失或填充的牙齿）、牙龈和简化口腔卫生指数、唾液流率、pH 值、缓冲能力、总蛋白和分泌型免疫球蛋白 A 浓度。

结果

JIA 患者的口腔卫生较差（P ≤.05），但龋齿和牙龈指数无差异。JIA 患者的总蛋白浓度增加（86%），pH 值为 6.9 至 6.0 范围内的缓冲能力增加（10%），初始 pH 值降低（6%），pH 值≥7.0 范围内的缓冲能力降低（50%），免疫球蛋白 A 浓度降低（27%）（P ≤.05）。