Department of Anesthesiology, Mayo College of Medicine, Rochester, MN, United States.
Department of Psychiatry and Psychology, Mayo College of Medicine, Rochester, MN, United States.
Addict Behav. 2014 Mar;39(3):593-9. doi: 10.1016/j.addbeh.2013.11.010. Epub 2013 Nov 21.
Current evidence suggests it may be difficult for patients with chronic pain to quit smoking and, based on previous formative work, a 7-session individual and group-based cognitive behavioral (CB) intervention was developed. The primary aim of this randomized controlled pilot trial was to test the hypothesis that abstinence at month 6 would be greater among patients with chronic pain who received the CB intervention compared to a control condition. Upon admission to a 3-week interdisciplinary pain treatment (IPT) program, patients were randomized to receive the CB intervention (n=30) or the control condition (n=30). The 7-day point prevalence of self-reported smoking status was assessed at week 3 (upon completion of the 3-week IPT program) and at month 6 in an intent-to-treat analysis. At week 3, 30% (n=9) of patients in the CB condition were abstinent from smoking compared to 10% (n=3) in the control group (P=.104). At month 6, 20% (n=6) of patients who received the CB intervention were abstinent compared to none in the control group (P=.024). At week 3, a significant group by time interaction effect was found where the CB patients experienced greater improvements in self-efficacy from baseline compared to the control group (P=.002). A greater proportion of patients randomized to the CB group completed the IPT program (P=.052). The findings of this pilot trial suggest that integration of a CB-based smoking abstinence intervention into ongoing pain therapy may be an effective treatment for smokers with chronic pain.
目前的证据表明,慢性疼痛患者戒烟可能较为困难。基于之前的基础工作,开发了一个 7 节的个体和团体认知行为(CB)干预措施。这项随机对照试验的主要目的是检验这样一个假设,即在接受 CB 干预的慢性疼痛患者中,与对照组相比,在第 6 个月时的戒烟率更高。在进入为期 3 周的跨学科疼痛治疗(IPT)计划时,患者被随机分配接受 CB 干预(n=30)或对照组(n=30)。在第 3 周(完成 3 周 IPT 计划后)和第 6 个月(意向治疗分析)时,通过 7 天的点患病率评估自我报告的吸烟状况。在第 3 周,CB 组中有 30%(n=9)的患者戒烟,而对照组中只有 10%(n=3)(P=.104)。在第 6 个月,接受 CB 干预的患者中有 20%(n=6)的患者戒烟,而对照组中没有患者(P=.024)。在第 3 周,发现了一个显著的组间时间交互效应,CB 患者的自我效能从基线开始比对照组有更大的改善(P=.002)。更多被随机分配到 CB 组的患者完成了 IPT 计划(P=.052)。这项试验的结果表明,将基于 CB 的戒烟干预措施纳入现有的疼痛治疗可能是治疗慢性疼痛吸烟者的有效方法。