Maurer B
Klinik für Rheumatologie, Universitätsspital Zürich, Gloriastr. 25, 8091, Zürich, Schweiz,
Z Rheumatol. 2013 Dec;72(10):970-6. doi: 10.1007/s00393-013-1196-8.
The early diagnosis of rheumatic diseases is becoming increasingly important. This particularly includes inflammatory myopathies which are multisystemic disorders with visceral involvement that are associated with high morbidity and mortality. Early diagnosis before the development of irreversible organ involvement is, therefore, of great importance.
This report provides information on early signs and symptoms of dermatomyositis and antisynthetase syndrome. Furthermore, screening methods which allow early diagnosis including involvement of internal organs are discussed. In addition, clinical and serological subtypes and their impact on prognosis are described.
风湿性疾病的早期诊断变得越来越重要。这尤其包括炎性肌病，它们是伴有内脏受累的多系统疾病，与高发病率和死亡率相关。因此，在不可逆器官受累发生之前进行早期诊断非常重要。
本报告提供了关于皮肌炎和抗合成酶综合征早期体征和症状的信息。此外，还讨论了能够实现早期诊断（包括内脏受累情况）的筛查方法。此外，还描述了临床和血清学亚型及其对预后的影响。
