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LED发射对心肌血运重建术后胸骨切开术切口修复的影响:一项随访的随机双盲研究。

The effects of LED emissions on sternotomy incision repair after myocardial revascularization: a randomized double-blind study with follow-up.

作者信息

de Oliveira Rauirys Alencar, Fernandes Gilderlene Alves, Lima Andréa Conceição Gomes, Tajra Filho Antônio Dib, de Barros Araújo Raimundo, Nicolau Renata Amadei

机构信息

Lasertherapy and Photobiology Center, Research and Development Institute (IP&D), Universidade do Vale do Paraíba (UNIVAP), São Paulo, Brazil,

出版信息

Lasers Med Sci. 2014 May;29(3):1195-202. doi: 10.1007/s10103-013-1503-2. Epub 2013 Dec 14.

DOI:10.1007/s10103-013-1503-2
PMID:24337350
Abstract

This study aimed to analyze the effects of light-emitting diode (LED) therapy on sternotomy pain and healing in patients who underwent coronary artery bypass grafting (CABG). The patients were followed for 6 months after the surgery to determine their dehiscence. This study was conducted with 90 volunteers who electively submitted to CABG. The volunteers were randomly allocated into three different groups of equal size: LED (λ of 640 ± 20 nm and spatial average energy fluency of 1.2 J/cm(2) during hospitalization), placebo, or control. The outcomes assessed were pain when coughing by a visual analog scale (VAS) and the McGill questionnaire and sternotomy healing by clinical assessment and photographical register end interpretation. The LED group had better pain reduction, as indicated by both the VAS and the McGill questionnaire (number of words chosen and pain index) (p ≤ 0.05), on days 6 and 8 after hospital discharge compared to the placebo and control groups. One month after surgery, almost no individual mentioned pain when coughing. Three researchers blindly analyzed the incision photographs to determine hyperemia and wound closure, and they found that the LED group had both less hyperemia and less incision bleeding or dehiscence. The LED therapy (640 nm) had an analgesic effect on the sternotomies of patients who underwent CABG, increasing their incision healing and preventing dehiscence.

摘要

本研究旨在分析发光二极管(LED)疗法对接受冠状动脉旁路移植术(CABG)患者胸骨切开术后疼痛及愈合的影响。术后对患者进行6个月的随访以确定其切口裂开情况。本研究纳入了90例择期接受CABG的志愿者。志愿者被随机分为三组,每组人数相等:LED组(住院期间波长为640±20 nm,空间平均能量通量为1.2 J/cm²)、安慰剂组或对照组。评估的结果包括通过视觉模拟量表(VAS)和麦吉尔问卷评估咳嗽时的疼痛,以及通过临床评估和照片记录最终解读评估胸骨切开术的愈合情况。与安慰剂组和对照组相比,出院后第6天和第8天,LED组在VAS和麦吉尔问卷(所选词汇数量和疼痛指数)方面均显示出更好的疼痛减轻效果(p≤0.05)。术后1个月,几乎没有人提到咳嗽时疼痛。三名研究人员对切口照片进行盲法分析以确定充血情况和伤口闭合情况,发现LED组充血较少,切口出血或裂开也较少。LED疗法(640 nm)对接受CABG患者的胸骨切开术具有镇痛作用,可促进切口愈合并防止裂开。

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5
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