Oxford Eye Hospital, , Oxford, UK.
Br J Ophthalmol. 2014 Mar;98(3):302-4. doi: 10.1136/bjophthalmol-2013-304450. Epub 2013 Dec 12.
To determine the feasibility of Ultra wide-field intravenous fundus fluorescein angiography (UWF-IV-FFA) in infants.
A retrospective review of infants who underwent UWF-IV-FFA with the Optos P200MA was performed. The ability to capture different phases of the angiogram, the total image acquisition time and the presence of image artefacts were analysed.
Twelve infants with a variety of proliferative retinopathies underwent UWF-IV-FFA over a 7-month period. The mean age was 3.4 months (range 2-6 months) and the mean image acquisition time was 4 min (range 3-5). Pseudocolour fundus images and the venous, recirculation and late phases of UWF-IV-FFA were captured successfully in all infants (100%). Choroidal and arterial phases were captured in one (8.3%) and 10 (83.3%) infants, respectively. Image artefacts due to eyelashes and corneal desiccation occurred in nine (75%) and six (50%) infants, respectively. No adverse medical problems were noted.
We have shown that UWF-IV-FFA can be successfully and safely performed in infants using the Optos P200MA system. It is a feasible new alternative to RetCam for obtaining an IV-FFA in the outpatients setting.
确定超广角静脉眼底荧光素血管造影(UWF-IV-FFA)在婴儿中的可行性。
对使用 Optos P200MA 进行 UWF-IV-FFA 的婴儿进行回顾性分析。分析了捕获血管造影不同阶段的能力、总图像采集时间和图像伪影的存在。
在 7 个月的时间里,12 名患有各种增殖性视网膜病变的婴儿接受了 UWF-IV-FFA 检查。平均年龄为 3.4 个月(范围 2-6 个月),平均图像采集时间为 4 分钟(范围 3-5 分钟)。所有婴儿(100%)均成功捕获了伪彩眼底图像以及 UWF-IV-FFA 的静脉、再循环和晚期相。脉络膜和动脉相分别在 1 名(8.3%)和 10 名(83.3%)婴儿中捕获。由于睫毛和角膜干燥,分别在 9 名(75%)和 6 名(50%)婴儿中出现了图像伪影。未观察到不良医疗问题。
我们已经证明,使用 Optos P200MA 系统可以成功、安全地在婴儿中进行 UWF-IV-FFA。它是在门诊环境中获得 IV-FFA 的一种可行的新替代方法,优于 RetCam。