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通过贝叶斯模型对加泰罗尼亚截至2020年的癌症发病率和死亡率预测。

Cancer incidence and mortality projections up to 2020 in Catalonia by means of Bayesian models.

作者信息

Ribes J, Esteban L, Clèries R, Galceran J, Marcos-Gragera R, Gispert R, Ameijide A, Vilardell M L, Borras J, Puigdefabregas A, Buxó M, Freitas A, Izquierdo A, Borras J M

机构信息

Registre del Càncer de Catalunya, Pla Director d'Oncologia (GENCAT), IDIBELL, Hospital Duran i Reynals, Gran Via 199-203 1ª planta, L'Hospitalet de Llobregat, 08908, Barcelona, Spain,

出版信息

Clin Transl Oncol. 2014 Aug;16(8):714-24. doi: 10.1007/s12094-013-1140-z. Epub 2013 Dec 12.

Abstract

PURPOSE

To predict the burden of cancer in Catalonia by 2020 assessing changes in demography and cancer risk during 2010-2020.

METHODS/PATIENTS: Data were obtained from Tarragona and Girona cancer registries and Catalan mortality registry. Population age distribution was obtained from the Catalan Institute of Statistics. Predicted cases in Catalonia were estimated through autoregressive Bayesian age-period-cohort models.

RESULTS

There will be diagnosed 26,455 incident cases among men and 18,345 among women during 2020, which means an increase of 22.5 and 24.5 % comparing with the cancer incidence figures of 2010. In men, the increase of cases (22.5 %) can be partitioned in three components: 12 % due to ageing, 8 % due to increase in population size and 2 % due to cancer risk. In women, the role of each component was 9, 8 and 8 %, respectively. The increased risk is mainly expected to be observed in tobacco-related tumours among women and in colorectal and liver cancers among men. During 2010-2020 a mortality decline is expected in both sexes.

CONCLUSION

The expected increase of cancer incidence, mainly due to tobacco-related tumours in women and colorectal in men, reinforces the need to strengthen smoking prevention and the expansion of early detection of colorectal cancer in Catalonia.

摘要

目的

通过评估2010 - 2020年加泰罗尼亚地区人口统计学和癌症风险的变化,预测到2020年该地区的癌症负担。

方法/患者:数据来自塔拉戈纳和赫罗纳癌症登记处以及加泰罗尼亚死亡率登记处。人口年龄分布数据来自加泰罗尼亚统计局。加泰罗尼亚地区的预测病例数通过自回归贝叶斯年龄 - 时期 - 队列模型进行估计。

结果

2020年预计男性将有26455例新发病例,女性将有18345例,这意味着与2010年的癌症发病率相比,分别增加了22.5%和24.5%。在男性中,病例增加(22.5%)可分为三个部分:12%归因于老龄化,8%归因于人口规模增加,2%归因于癌症风险。在女性中,各部分的作用分别为9%、8%和8%。预计风险增加主要体现在女性与烟草相关的肿瘤以及男性的结直肠癌和肝癌中。2010 - 2020年期间,预计两性死亡率均会下降。

结论

预计癌症发病率会上升,主要是女性的烟草相关肿瘤和男性的结直肠癌,这进一步凸显了加泰罗尼亚加强吸烟预防以及扩大结直肠癌早期检测的必要性。

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