Kefer Joelle, Sluysmans Thierry, Vanoverschelde Jean-Louis
Cliniques Universitaires Saint-Luc, Université Catholique de Louvain, Division of Cardiology, Avenue Hippocrate 10-2881, Brussels, 1200, Belgium.
Catheter Cardiovasc Interv. 2014 Apr 1;83(5):841-5. doi: 10.1002/ccd.25330. Epub 2013 Dec 31.
We describe the first report of a transcatheter Sapien implantation in a native tricuspid valve after multiple failed surgical repairs with a lack of prosthetic material and radiographic landmarks.
A 47-year old female underwent multiple valve repairs and replacements including three tricuspid valve repairs without surgical ring or bioprosthesis implantation. She developed signs of right heart failure associated with a mixed tricuspid disease combining a severe stenosis and regurgitation. After surgical turn down, a revalvulation using a transcatheter approach was attempted. The challenges in this case were the absence of a stiff region to anchor the percutaneous valve, the lack of radiographic landmarks and the difficulties of precise annulus measurements. The applied strategy was -under general anesthesia and extracorporeal membrane oxygenation-: balloon sizing, prestenting of the tricuspid annulus using covered stents followed by Sapien valve implantation through the femoral vein under fluoroscopy and transoesophageal echocardiography (TEE). The procedure was successfull, solving the tricuspid leak and stenosis (peak gradient from 22 to 3 mm Hg) using two Sapien for a perfect positioning. It was complicated by pulmonary bleeding due to a distal wire exit, treated successfully by coil embolization. The clinical and echocardiographic outcome was good up to 5 months.
Transcatheter Sapien valve implantation in a native tricuspid valve after failed multiple surgical repairs is feasible by the femoral vein. Technical challenges due to the lack of rigid landing zone and fluoroscopic markers were solved by prestenting and valve implantation under bi-plane fluoroscopic and TEE guidance.
我们报告首例在多次外科修复失败且缺乏人工材料和影像学标志的情况下,经导管植入Sapien瓣膜至天然三尖瓣的病例。
一名47岁女性接受了多次瓣膜修复和置换手术,包括三次三尖瓣修复术,但均未植入手术环或生物假体。她出现了与严重狭窄和反流并存的混合性三尖瓣疾病相关的右心衰竭症状。在手术拒绝后,尝试采用经导管方法进行再次瓣膜置换。该病例的挑战在于缺乏用于固定经皮瓣膜的坚硬区域、缺乏影像学标志以及精确测量瓣环存在困难。所采用的策略是在全身麻醉和体外膜肺氧合支持下:进行球囊扩张,使用覆膜支架对三尖瓣环进行预扩张,随后在荧光透视和经食管超声心动图(TEE)引导下经股静脉植入Sapien瓣膜。手术成功,通过使用两个Sapien瓣膜实现完美定位,解决了三尖瓣反流和狭窄问题(峰值压差从22 mmHg降至3 mmHg)。手术出现并发症,因远端导丝穿出导致肺出血,通过弹簧圈栓塞成功治疗。至5个月时临床和超声心动图结果良好。
在多次外科修复失败后,经股静脉将Sapien瓣膜经导管植入天然三尖瓣是可行的。通过预扩张以及在双平面荧光透视和TEE引导下植入瓣膜,解决了因缺乏刚性着陆区和荧光透视标记所带来的技术挑战。