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一名免疫功能低下男性的小肠三重原生动物肠道病:一份罕见的组织病理学报告。

Triple protozoal enteropathy of the small intestine in an immunocompromised male: A rare histopathology report.

作者信息

Malik Ajay, Kulaar Janmeet, Shukla Rajat, Dutta Vibha

机构信息

Department of Pathology, Armed Forces Medical College, Pune, India.

出版信息

Indian J Sex Transm Dis AIDS. 2013 Jul;34(2):119-22. doi: 10.4103/0253-7184.120548.

Abstract

Enteric protozoan parasites remain the most commonly encountered parasitic diseases in HIV infected patients. Opportunistic protozoal infections that infect GIT most commonly and cause diarrhea in HIV-infected patients are cryptosporidium parvum, microsporidia and Isospora belli. Developing an infection with enteric protozoan parasites is dependent on absolute CD4+ cell counts, with lower counts associated with more severe, more atypical disease, and a greater risk of disseminated disease. We present histopathological features in a patient, where all three parasitic infections co-existed in HIV infected patient, who was under antitubercular therapy in addition to antiretroviral therapy and herpes zoster infection being treated by acyclovir.

摘要

肠道原生动物寄生虫仍然是HIV感染患者中最常见的寄生虫病。最常感染胃肠道并导致HIV感染患者腹泻的机会性原生动物感染是微小隐孢子虫、微孢子虫和贝氏等孢球虫。发生肠道原生动物寄生虫感染取决于绝对CD4+细胞计数,计数越低,疾病越严重、越不典型,播散性疾病的风险也越大。我们展示了一名患者的组织病理学特征,该HIV感染患者同时存在这三种寄生虫感染,除抗逆转录病毒治疗外,该患者还在接受抗结核治疗,并且正在用阿昔洛韦治疗带状疱疹感染。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c8aa/3841662/f282e409d78b/IJSTD-34-119-g001.jpg

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