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Use- and voltage-dependent block of the sodium channel by saxitoxin.

作者信息

Salgado V L, Yeh J Z, Narahashi T

出版信息

Ann N Y Acad Sci. 1986;479:84-95. doi: 10.1111/j.1749-6632.1986.tb15563.x.

DOI:10.1111/j.1749-6632.1986.tb15563.x
PMID:2434010
Abstract
摘要

相似文献

1
Use- and voltage-dependent block of the sodium channel by saxitoxin.石房蛤毒素对钠通道的使用和电压依赖性阻滞
Ann N Y Acad Sci. 1986;479:84-95. doi: 10.1111/j.1749-6632.1986.tb15563.x.
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Structure-activity relations of tetrodotoxin, saxitoxin, and analogues.
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4
Kinetics of TTX-STX block of sodium channels.河豚毒素-石房蛤毒素对钠通道的阻断动力学
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Saxitoxin and tetrodotoxin. Electrostatic effects on sodium channel gating current in crayfish axons.石房蛤毒素和河豚毒素。小龙虾轴突中静电对钠通道门控电流的影响。
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6
Active groups of saxitoxin and tetrodotoxin as deduced from actions of saxitoxin analogues on frog muscle and squid axon.从石房蛤毒素类似物对蛙肌和乌贼轴突的作用推导石房蛤毒素和河豚毒素的活性基团。
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Spatial relations of the neurotoxin binding sites on the sodium channel.钠通道上神经毒素结合位点的空间关系。
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8
Pharmacological properties of axonal sodium channels in the cockroach Periplaneta americana L. I. Selective block by synthetic saxitoxin.美洲大蠊轴突钠通道的药理学特性。I. 合成石房蛤毒素的选择性阻断
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9
Saxitoxin blocks batrachotoxin-modified sodium channels in the node of Ranvier in a voltage-dependent manner.石房蛤毒素以电压依赖性方式阻断郎飞结处经蟾毒素修饰的钠通道。
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On the mechanism by which saxitoxin binds to and blocks sodium channels.关于石房蛤毒素结合并阻断钠通道的机制。
Ann N Y Acad Sci. 1986;479:96-112. doi: 10.1111/j.1749-6632.1986.tb15564.x.

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The outer vestibule of the Na+ channel-toxin receptor and modulator of permeation as well as gating.钠离子通道毒素受体及通透性和门控调节剂的外前庭。
Mar Drugs. 2010 Apr 21;8(4):1373-93. doi: 10.3390/md8041373.
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Beta1-subunit modulates the Nav1.4 sodium channel by changing the surface charge.β1亚基通过改变表面电荷来调节Nav1.4钠通道。
Exp Brain Res. 2006 Jun;172(2):139-50. doi: 10.1007/s00221-005-0323-4. Epub 2006 Jan 24.
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Tonic and phasic guanidinium toxin-block of skeletal muscle Na channels expressed in Mammalian cells.哺乳动物细胞中表达的骨骼肌钠通道的强直和相位胍盐毒素阻断作用。
Biophys J. 2003 May;84(5):2999-3006. doi: 10.1016/S0006-3495(03)70026-5.
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Tonic and phasic tetrodotoxin block of sodium channels with point mutations in the outer pore region.在外孔区域存在点突变的钠通道的强直性和阶段性河豚毒素阻断
Biophys J. 1999 Jul;77(1):229-40. doi: 10.1016/S0006-3495(99)76884-0.
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Use dependence of tetrodotoxin block of sodium channels: a revival of the trapped-ion mechanism.河豚毒素对钠通道阻滞的使用依赖性:俘获离子机制的复兴。
Biophys J. 1996 Sep;71(3):1295-312. doi: 10.1016/S0006-3495(96)79330-X.
9
Divalent cation competition with [3H]saxitoxin binding to tetrodotoxin-resistant and -sensitive sodium channels. A two-site structural model of ion/toxin interaction.二价阳离子与[3H]石房蛤毒素结合对河豚毒素抗性和敏感性钠通道的影响。离子/毒素相互作用的双位点结构模型。
J Gen Physiol. 1993 Feb;101(2):153-82. doi: 10.1085/jgp.101.2.153.
10
Post-repolarization block of cardiac sodium channels by saxitoxin.石房蛤毒素对心脏钠通道的复极化后阻滞作用。
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