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病灶内注射类固醇以预防浅表食管癌近环周内镜黏膜下剥离术后狭窄。

Intralesional steroid injection to prevent stricture after near-circumferential endosopic submucosal dissection for superficial esophageal cancer.

作者信息

Lee Wook Jin, Jung Hwoon-Yong, Kim Do Hoon, Lee Jeong Hoon, Choi Kee Don, Song Ho June, Lee Gin Hyug, Kim Jin-Ho

机构信息

Department of Gastroenterology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.

出版信息

Clin Endosc. 2013 Nov;46(6):643-6. doi: 10.5946/ce.2013.46.6.643. Epub 2013 Nov 19.

DOI:10.5946/ce.2013.46.6.643
PMID:24340258
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3856266/
Abstract

Stricture frequently occurs after endoscopic submucosal dissection (ESD) for superficial esophageal carcinoma with near- or whole-circumferential mucosal defects, and post-ESD stricture is difficult to treat and usually requires multiple sessions of endoscopic balloon dilatation. Intralesional steroid injection has previously been used to prevent stricture; however, there have been few experiences with this method after near- or whole-circumferential ESD. We present a case of a single session of intralesional steroid injection performed immediately after near-circumferential ESD to prevent post-ESD stricture. After a follow-up period of 6 months, the patient showed good outcome without dysphagia.

摘要

对于伴有近全周或全周黏膜缺损的浅表食管癌，在内镜黏膜下剥离术（ESD）后狭窄经常发生，且ESD术后狭窄难以治疗，通常需要多次进行内镜球囊扩张。病灶内注射类固醇以前曾用于预防狭窄；然而，在近全周或全周ESD后使用这种方法的经验很少。我们报告1例在近全周ESD后立即进行单次病灶内注射类固醇以预防ESD术后狭窄的病例。经过6个月的随访期，患者预后良好，无吞咽困难。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d30/3856266/15e1fdb25a2d/ce-46-643-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d30/3856266/02e056346cee/ce-46-643-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d30/3856266/15e1fdb25a2d/ce-46-643-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d30/3856266/02e056346cee/ce-46-643-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d30/3856266/15e1fdb25a2d/ce-46-643-g002.jpg

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Management of esophageal stricture after complete circular endoscopic submucosal dissection for superficial esophageal squamous cell carcinoma.
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