Clouth A, Schöfer H
Department of Dermatology, Venereology, and Allergology, J.W. Goethe University, Frankfurt/M, Germany.
J Eur Acad Dermatol Venereol. 2015 Jan;29(1):178-9. doi: 10.1111/jdv.12341. Epub 2013 Dec 17.
Facial verrucae vulgares are benign, but disfiguring skin manifestations of human papilloma virus infection. They are found as verrucae planae juveniles in young adults, but also as common warts in immunocompromised or atopic patients.
To find an alternative, non-surgical treatment for a young man with atopic dermatitis and facial warts, who had not responded to 5-FU ointment, waterfiltered infrared A (wIRA) irradiation and topical retinoids.
Topical treatment with a sinecatechins 10% ointment (Veregen(TM) ) as approved for genital warts thrice daily for 3 weeks in a 34-year-old man with atopic dermatitis
Complete remission of all facial warts was achieved within 20 days. Few side-effects were observed (initially some light skin irritation only).
In this case, topical sinecatechins proved to be a well-tolerated and effective alternative to treat recalcitrant facial warts without surgery.
面部寻常疣是由人乳头瘤病毒感染引起的良性但毁容性皮肤表现。在年轻人中表现为扁平疣,在免疫功能低下或特应性患者中则表现为普通疣。
为一名患有特应性皮炎且面部有疣、对5-氟尿嘧啶软膏、水过滤红外A(wIRA)照射和外用维甲酸治疗无效的年轻男性寻找一种非手术替代治疗方法。
对一名34岁患有特应性皮炎的男性患者,使用已获批用于治疗尖锐湿疣的10%儿茶素软膏(Veregen™)进行局部治疗,每日三次,持续3周。
20天内所有面部疣完全消退。观察到的副作用很少(最初仅有一些轻微的皮肤刺激)。
在这种情况下,局部使用儿茶素被证明是一种耐受性良好且有效的非手术替代方法,可用于治疗顽固性面部疣。