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饮食失调的有效治疗:多中心研究结果。

Effective treatment of eating disorders: Results at multiple sites.

作者信息

Bergh Cecilia, Callmar Monica, Danemar Sophia, Hölcke Mats, Isberg Susanne, Leon Michael, Lindgren Jessica, Lundqvist Asa, Niinimaa Maria, Olofsson Barbro, Palmberg Karolina, Pettersson Anna, Zandian Modjtaba, Asberg Kajsa, Brodin Ulf, Maletz Louis, Court John, Iafeta Iva, Björnström Mikael, Glantz Caroline, Kjäll Linda, Rönnskog Pia, Sjöberg Jennie, Södersten Per

机构信息

Mandometer Clinic.

Section of Medical Statistics.

出版信息

Behav Neurosci. 2013 Dec;127(6):878-89. doi: 10.1037/a0034921.

Abstract

We report the results of a study based on 1,428 patients with eating disorders treated at 6 clinics. These patients were consecutively referred over 18 years and used inpatient and outpatient treatment. The subjects were diagnosed with anorexia nervosa, bulimia nervosa, or an eating disorder not otherwise specified. Patients practiced a normal eating pattern with computerized feedback technology, they were supplied with external heat, their physical activity was reduced, and their social habits restored to allow them to return to their normal life. The estimated rate of remission for this therapy was 75% after a median of 12.5 months of treatment. A competing event such as the termination of insurance coverage, or failure of the treatment, interfered with outcomes in 16% of the patients, and the other patients remained in treatment. Of those who went in remission, the estimated rate of relapse was 10% over 5 years of follow-up and there was no mortality. These data replicate the outcomes reported in our previous studies and they compare favorably with the poor long-term remission rates, the high rate of relapse, and the high mortality rate reported with standard treatments for eating disorders.

摘要

我们报告了一项基于在6家诊所接受治疗的1428例饮食失调患者的研究结果。这些患者在18年期间被连续转诊,并接受了住院和门诊治疗。受试者被诊断为神经性厌食症、神经性贪食症或未另行指明的饮食失调症。患者通过计算机化反馈技术采用正常饮食模式,接受外部供热,减少身体活动,并恢复社交习惯,以便能够回归正常生活。经过中位数为12.5个月的治疗后,该疗法的估计缓解率为75%。诸如保险覆盖终止或治疗失败等竞争事件干扰了16%患者的治疗结果,其他患者仍在接受治疗。在实现缓解的患者中,随访5年的估计复发率为10%,且无死亡病例。这些数据重复了我们之前研究报告的结果,并且与饮食失调症标准治疗所报告的较差长期缓解率、高复发率和高死亡率相比更具优势。

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