进食障碍的病程和结局更新。
Update on course and outcome in eating disorders.
机构信息
Department of Psychology, Florida State University, Tallahassee, Florida 32306, USA.
出版信息
Int J Eat Disord. 2010 Apr;43(3):195-204. doi: 10.1002/eat.20810.
OBJECTIVE
To review recent studies describing eating disorder course and outcome.
METHOD
Electronic and manual searches were conducted to identify relevant articles published since 2004.
RESULTS
Twenty-six articles were identified. For anorexia nervosa (AN), most patients ascertained through outpatient settings achieved remission by 5-year follow-up. Inpatient treatment predicted poor prognosis as inpatient samples demonstrated lower remission rates. Outcome differed between bulimia nervosa (BN) and eating disorders not otherwise specified (EDNOS), including binge eating disorder (BED), for shorter follow-up durations; however, outcomes appeared similar between BN and related EDNOS by 5-year follow-up. Greater psychiatric comorbidity emerged as a significant predictor of poor prognosis in BN, whereas few prognostic indicators were identified for BED or other EDNOS.
DISCUSSION
Results support optimism for most patients with eating disorders. However, more effective treatments are needed for adult AN inpatients and approximately 30% of patients with BN and related EDNOS who remain ill 10-20 years following presentation.
目的
综述近期有关进食障碍病程和结局的研究。
方法
电子和手动检索 2004 年以来发表的相关文章。
结果
共确定了 26 篇文章。对于神经性厌食症（AN），通过门诊随访，大多数患者在 5 年随访时达到缓解。住院治疗预示着预后较差，因为住院样本的缓解率较低。在较短的随访时间内，神经性贪食症（BN）和未特定的进食障碍（EDNOS），包括暴食障碍（BED）的结局不同；然而，在 5 年随访时，BN 和相关的 EDNOS 之间的结局似乎相似。精神共病的增加是 BN 预后不良的一个重要预测因素，而 BED 或其他 EDNOS 则很少有预后指标。
讨论
结果支持对大多数进食障碍患者持乐观态度。然而，对于成年 AN 住院患者以及大约 30%的 BN 和相关 EDNOS 患者，需要更有效的治疗，这些患者在出现症状后 10-20 年仍未康复。
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