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罗马尼亚连续且未经筛查人群中巴氏涂片异常的流行情况。

Prevalence of abnormal Pap smears in a consecutive and previously unscreened population in Romania.

机构信息

Department of Pathology, University of Medicine Targu Mures, Targu Mures, Romania; Histopat-Invest Laboratory, Targu Mures, Romania.

Citos Laboratory, Iasi, Romania.

出版信息

Int J Gynaecol Obstet. 2014 Feb;124(2):156-9. doi: 10.1016/j.ijgo.2013.07.030. Epub 2013 Oct 17.

Abstract

OBJECTIVE

To determine the prevalence of abnormal cervical smears in a previously unscreened and asymptomatic population in Romania and to compare the data with those from other countries in Europe.

METHODS

In a retrospective study, data were reviewed from smears obtained from women in Romania who had been referred to the gynecologist between January 2006 and December 2011. The smears were collected through 3 regional opportunistic programs of cervical screening and were classified according to the Bethesda system.

RESULTS

During the study period, 50536 smear tests were carried out. Of these, 100 smears (0.2%) were unsatisfactory and excluded from the study. Among the remaining 50436 smears, 2965 patients (5.9%) had abnormal epithelial changes. Most of the abnormal smears were represented by atypical squamous cells of undetermined significance (2.6% of all smears). The data confirmed that there is a high prevalence of high-grade intraepithelial squamous-type lesions (0.9% of all smears) in Romania, and of abnormal smears in women younger than 25years of age (14.0% of all abnormal smears).

CONCLUSION

The data show that there is a high prevalence of epithelial abnormalities among cervical smears in Romania compared with other European countries that run a national screening program.

摘要

目的

确定罗马尼亚一个未经筛查且无症状人群中异常宫颈涂片的流行率,并将数据与欧洲其他国家进行比较。

方法

在一项回顾性研究中,对罗马尼亚于 2006 年 1 月至 2011 年 12 月期间转诊至妇科医生的妇女进行了涂片检查。这些涂片是通过 3 个区域性机会性宫颈癌筛查计划收集的,并根据巴氏系统进行了分类。

结果

在研究期间,共进行了 50536 次涂片检查。其中,100 份涂片(0.2%)不满意,被排除在研究之外。在剩余的 50436 份涂片检查中,有 2965 例患者(5.9%)有异常上皮变化。大多数异常涂片是意义不明的非典型鳞状细胞(所有涂片的 2.6%)。数据证实罗马尼亚存在高级别上皮内鳞状型病变(所有涂片的 0.9%)和 25 岁以下妇女异常涂片(所有异常涂片的 14.0%)的高患病率。

结论

与开展全国性筛查计划的其他欧洲国家相比,罗马尼亚的宫颈涂片上皮异常的流行率较高。

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