College of Horticulture, Nanjing Agricultural University, Nanjing 210095, China.
College of Horticulture, Nanjing Agricultural University, Nanjing 210095, China.
Gene. 2014 Feb 25;536(2):416-24. doi: 10.1016/j.gene.2013.10.059. Epub 2013 Dec 14.
The FKBP protein family has prolyl isomerase activity and is related in function to cyclophilins. FKBPs are known to be involved in many biological processes including hormone signaling, plant growth, and stress responses through a chaperone or an isomerization of proline residues during protein folding. The availability of complete peach genome sequences allowed the identification of 21 FKBP genes by HMMER and BLAST analyses. Scaffold locations of these FKBP genes in the peach genome were determined and the protein domain and motif organization of peach FKBPs were analyzed. The phylogenetic relationships between peach FKBPs were also assessed. The expression profiles of peach FKBP gene results revealed that most peach FKBPs were expressed in all tissues, while a few peach FKBPs were specifically expressed in some of the tissues. This data could contribute to better understanding of the complex regulation of the peach FKBP gene family, and also provide valuable information for further research in peach functional genomics.
FKBP 蛋白家族具有脯氨酰异构酶活性，在功能上与亲环素相关。FKBP 已知参与许多生物学过程，包括激素信号转导、植物生长和应激反应，通过伴侣蛋白或在蛋白质折叠过程中脯氨酸残基的异构化。完整桃基因组序列的可用性允许通过 HMMER 和 BLAST 分析鉴定 21 个 FKBP 基因。确定了这些 FKBP 基因在桃基因组中的支架位置，并分析了桃 FKBPs 的蛋白结构域和基序组织。还评估了桃 FKBPs 之间的系统发育关系。桃 FKBP 基因的表达谱结果表明，大多数桃 FKBP 在所有组织中表达，而少数桃 FKBP 在一些组织中特异性表达。这些数据有助于更好地理解桃 FKBP 基因家族的复杂调控，并为桃功能基因组学的进一步研究提供有价值的信息。
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