Yosef-Brauner Orna, Adi Nimrod, Ben Shahar Tamar, Yehezkel Ester, Carmeli Eli
Physical Therapy Department, Kaplan Medical Center, Rehovot, Israel.
Clin Respir J. 2015 Jan;9(1):1-6. doi: 10.1111/crj.12091. Epub 2014 Jan 10.
The aim of this study was to evaluate the effect of an intensive physical therapy protocol in patients who contract 'intensive care unit-acquired weakness' (ICUAW), in terms of muscle strength, breathing and functional indices.
This was a prospective, single-blinded study in a general hospital intensive care unit (ICU). Patients who required mechanical ventilation longer than 48 h and who were expected to remain mechanically ventilated for at least another 48 h were randomly divided into two intervention groups: group I (n = 9) - the routine care group, received physical therapy according to our daily custom protocol; and group II (n = 9) - the intensive treatment group, were treated by the same protocol twice a day. The main outcome measures included the Medical Research Council (MRC) physical strength examination, maximal inspiratory pressure (MIP), hand grip dynamometer and sitting balance test.
Significant strength improvement from first (T1) to second (T2) measurements was demonstrated for variables MIP and MRC physical strength examination in favor of the intensive treatment group (P < 0.05). The intensive treatment group also required shorter intensive care length of stay than the routine care group (P = 0.043).
It is possible that an intensive therapy protocol may facilitate the initial recovery process in patients who suffer from ICUAW.
本研究旨在评估强化物理治疗方案对患有“重症监护病房获得性肌无力”(ICUAW)患者的肌肉力量、呼吸和功能指标的影响。
这是一项在综合医院重症监护病房(ICU)进行的前瞻性单盲研究。需要机械通气超过48小时且预计至少再进行48小时机械通气的患者被随机分为两个干预组:第一组(n = 9)——常规护理组,按照我们日常的常规方案接受物理治疗;第二组(n = 9)——强化治疗组,每天按照相同方案接受两次治疗。主要结局指标包括医学研究委员会(MRC)体力检查、最大吸气压力(MIP)、握力计和坐位平衡测试。
对于变量MIP和MRC体力检查,从第一次(T1)测量到第二次(T2)测量,强化治疗组的力量有显著改善(P < 0.05)。强化治疗组的重症监护住院时间也比常规护理组短(P = 0.043)。
强化治疗方案可能有助于患有ICUAW的患者的初始恢复过程。