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麻醉学实践中的低血糖:诊断、预防及管理策略

Hypoglycaemia in anesthesiology practice: Diagnostic, preventive, and management strategies.

作者信息

Kalra Sanjay, Bajwa Sukhminder Jit Singh, Baruah Manash, Sehgal Vishal

机构信息

Department of Endocrinology, Bharti Hospital and BRIDE, Karnal, Haryana, India.

Department of Anaesthesiology and Intensive Care, Gian Sagar Medical College and Hospital, Ram Nagar, Banur, Punjab, India.

出版信息

Saudi J Anaesth. 2013 Oct;7(4):447-52. doi: 10.4103/1658-354X.121082.

DOI:10.4103/1658-354X.121082
PMID:24348299
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3858698/
Abstract

Diabetes mellitus has emerged as one of the fastest growing non communicable diseases worldwide. Management of diabetic patients during surgical and critically illness is of paramount challenge to anesthesiologist and intensivist. Among its major acute complications, hypoglycemia has been given lesser attention as compared to other major acute complications; diabetic ketoacidosis and hyperosmolar non ketotic coma. However, newer studies and literary evidence have established the serious concerns of morbidity and mortality, both long- and short-term, related to hypoglycemia. basis. Invariably, diabetic patients are encountered in our daily routine practice of anesthesia. During fasting status as well as the perioperative period, it is hypoglycemia that is of high concern to anesthesiologist. Management has to be based on clinical, pharmacological, social, and psychological basis, so as to completely prevent the complications arising from an acute episode of hypoglycemia. This review aims to highlight various aspects of hypoglycemia and its management both from endocrine and anesthesia perspective.

摘要

糖尿病已成为全球增长最快的非传染性疾病之一。在外科手术和危重病期间对糖尿病患者的管理,对麻醉医生和重症监护医生来说是一项至关重要的挑战。在其主要的急性并发症中,与其他主要急性并发症(糖尿病酮症酸中毒和高渗性非酮症昏迷)相比,低血糖受到的关注较少。然而,最新的研究和文献证据已经证实了低血糖在短期和长期内与发病率和死亡率相关的严重问题。在我们日常的麻醉实践中,糖尿病患者总是会遇到。在禁食状态以及围手术期,麻醉医生高度关注的是低血糖。管理必须基于临床、药理学、社会和心理学基础,以完全预防低血糖急性发作引起的并发症。本综述旨在从内分泌和麻醉角度突出低血糖及其管理的各个方面。

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本文引用的文献

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Diabeto-anaesthesia: A subspecialty needing endocrine introspection.糖尿病麻醉:一个需要内分泌领域反思的亚专业。
Indian J Anaesth. 2012 Nov;56(6):513-7. doi: 10.4103/0019-5049.104564.
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Usage pattern, glycemic improvement, hypoglycemia, and body mass index changes with sulfonylureas in real-life clinical practice: results from OBSTACLE Hypoglycemia Study.在真实临床实践中使用磺脲类药物的模式、血糖改善、低血糖和体重指数变化:来自 OBSTACLE 低血糖研究的结果。
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Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010.1990年和2010年20个年龄组中235种死因的全球和区域死亡率:全球疾病负担研究2010的系统分析
Lancet. 2012 Dec 15;380(9859):2095-128. doi: 10.1016/S0140-6736(12)61728-0.
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Intensive care management of critically sick diabetic patients.危重症糖尿病患者的重症监护管理
Indian J Endocrinol Metab. 2011 Oct;15(4):349-50. doi: 10.4103/2230-8210.85603.
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Treatment of severe diabetic hypoglycemia with glucagon: an underutilized therapeutic approach.用胰高血糖素治疗严重糖尿病性低血糖:一种未充分利用的治疗方法。
Diabetes Metab Syndr Obes. 2011;4:337-46. doi: 10.2147/DMSO.S20633. Epub 2011 Sep 6.
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Medically minimising the impact of hypoglycaemia in type 2 diabetes: a review.医学上最大限度减少 2 型糖尿病低血糖的影响:综述。
Expert Opin Pharmacother. 2011 Oct;12(14):2161-75. doi: 10.1517/14656566.2011.589835. Epub 2011 Jun 14.
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Postgrad Med J. 2011 Apr;87(1026):298-306. doi: 10.1136/pgmj.2008.068197. Epub 2011 Feb 4.
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Association between glucose variability and adverse in-hospital outcomes for Chinese patients with acute coronary syndrome.中国急性冠状动脉综合征患者血糖变异性与不良院内结局之间的关联。
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Glycaemic fluctuation predicts mortality in critically ill patients.血糖波动可预测危重症患者的死亡率。
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Hypoglycemia is associated with intensive care unit mortality.低血糖与重症监护病房死亡率有关。
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