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莫比乌斯综合征：眼睑功能障碍的外科治疗

Möbius syndrome: surgical treatment for eyelid dysfunction.

作者信息

Lopez-Valverde Gloria, Jarrin-Hernandez Elena, Cruz-Gonzalez Fernando, Mateos-Sanchez Encarnacion

机构信息

Servicio de Oftalmología, Sección de Oculoplástica y Dacriología, Hospital Universitario Ramón y Cajal, Madrid, Spain.

出版信息

Case Rep Ophthalmol. 2013 Nov 5;4(3):229-33. doi: 10.1159/000356528. eCollection 2013.

DOI:10.1159/000356528
PMID:24348407
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3843936/
Abstract

INTRODUCTION

Möbius syndrome is a heterogeneous congenital disorder that is linked to bilateral palsies of the cranial nerves VI and VII, resulting in congenital facial paralysis sometimes associated with impaired ocular abduction.

CASE REPORT

We present the case of a 44-year-old woman with Möbius syndrome and inferior recurrent keratitis secondary to scleral show in both eyes. We decided to use a cartilage graft from the ear in the inferior eyelid to avoid eyelid retraction and scleral show.

DISCUSSION

Patients with Möbius syndrome have a severe dysfunction of their facial mimic. Their treatment must be individualized, depending on their age, clinical examination and symptoms.

摘要

引言

莫比乌斯综合征是一种异质性先天性疾病，与双侧第六和第七颅神经麻痹有关，导致先天性面瘫，有时伴有眼球外展障碍。

病例报告

我们报告一例44岁患有莫比乌斯综合征的女性患者，双眼因巩膜暴露继发下角膜反复发炎。我们决定在下眼睑使用耳部软骨移植来避免眼睑退缩和巩膜暴露。

讨论

莫比乌斯综合征患者面部表情严重功能障碍。其治疗必须个体化，取决于患者年龄、临床检查及症状。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/79b2/3843936/122f8293f6c2/cop-0004-0229-g03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/79b2/3843936/5a7e00e78838/cop-0004-0229-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/79b2/3843936/39aa7d4fdb38/cop-0004-0229-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/79b2/3843936/122f8293f6c2/cop-0004-0229-g03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/79b2/3843936/5a7e00e78838/cop-0004-0229-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/79b2/3843936/39aa7d4fdb38/cop-0004-0229-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/79b2/3843936/122f8293f6c2/cop-0004-0229-g03.jpg

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Möbius syndrome: surgical treatment for eyelid dysfunction.莫比乌斯综合征：眼睑功能障碍的外科治疗
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引用本文的文献

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Moebius Syndrome: An Updated Review of Literature.梅比厄斯综合征：文献综述更新
Child Neurol Open. 2023 Oct 18;10:2329048X231205405. doi: 10.1177/2329048X231205405. eCollection 2023 Jan-Dec.

本文引用的文献

1
Congenital Paralysis of Both Abducens and Both Facial Nerves.先天性双侧展神经和面神经麻痹
Trans Am Ophthalmol Soc. 1881;3:216-8.
2
Functional and aesthetic approach to adult unoperated Möbius syndrome: orthognathic surgery followed by bilateral free gracilis muscle transfers.成人未手术治疗的莫比乌斯综合征的功能与美学治疗方法：正颌手术联合双侧游离股薄肌移植术
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Free tissue transfer for the treatment of facial paralysis.游离组织移植治疗面瘫。
Facial Plast Surg. 2008 May;24(2):194-203. doi: 10.1055/s-2008-1075834.
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[Möbius syndrome: ocular and clinical manifestations].[莫比乌斯综合征：眼部及临床表现]
J Fr Ophtalmol. 2007 Feb;30(2):177-82. doi: 10.1016/s0181-5512(07)89570-2.
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Surgical correction of unilateral and bilateral facial palsy.单侧和双侧面瘫的手术矫正。
Postgrad Med J. 2005 Sep;81(959):562-7. doi: 10.1136/pgmj.2004.020321.
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Autogenous fascia lata grafts: clinical applications in reanimation of the totally or partially paralyzed face.自体阔筋膜移植：在完全或部分面瘫修复中的临床应用
Plast Reconstr Surg. 2005 Jul;116(1):20-32; discussion 33-5. doi: 10.1097/01.prs.0000169685.54862.18.
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Congenital abnormalities of cranial nerve development: overview, molecular mechanisms, and further evidence of heterogeneity and complexity of syndromes with congenital limitation of eye movements.颅神经发育的先天性异常：概述、分子机制以及眼球运动先天性受限综合征异质性和复杂性的更多证据。
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Outcomes with eye reanimation microsurgery.眼部重建显微手术的治疗效果。
Facial Plast Surg. 2002 May;18(2):101-12. doi: 10.1055/s-2002-32200.