Hirata Akira, Mine Tadashi
Department of Ophthalmology, Saga University Faculty of Medicine, Saga, Japan.
Case Rep Ophthalmol. 2013 Nov 6;4(3):238-42. doi: 10.1159/000356126. eCollection 2013.
Peters' anomaly is characterized by a central corneal opacity with corresponding defects in the posterior stroma, Descemet's membrane, and endothelium. We present 2 cases that showed corneal opacity when examined by topical endoscopic imaging (TEI). Case 1 was a 20-day-old neonatal female who had a central corneal opacity in the left eye. TEI showed that the iris stroma was adhered toward the back of the opacified cornea. Case 2 was a 4-month-old male who had a bilateral corneal opacity. TEI revealed that both a keratolenticular adhesion and a surrounding iridocorneal adhesion were observed behind the area of corneal opacity. The patient was diagnosed as having Peters' anomaly with persistent fetal vasculature. This study demonstrates that TEI is a novel method capable of looking into an eye from only a small area of the clear cornea.
彼得斯异常的特征是中央角膜混浊，伴有后弹力层、Descemet膜和内皮细胞的相应缺损。我们报告2例经局部内镜成像（TEI）检查时显示角膜混浊的病例。病例1是一名20日龄的新生儿女性，左眼有中央角膜混浊。TEI显示虹膜基质附着于混浊角膜的后部。病例2是一名4个月大的男性，双眼角膜混浊。TEI显示在角膜混浊区域后方观察到角膜晶状体粘连和周围虹膜角膜粘连。该患者被诊断为患有伴有永存胎儿血管的彼得斯异常。本研究表明，TEI是一种能够仅从透明角膜的小区域观察眼内情况的新方法。
